Optimization of pre‐analytical and analytical steps for DNA and RNA analysis of fresh cytology samples
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4728
Abstract: Different cytology preparations can be used for molecular diagnostics, however the influence of pre‐analytical and analytical steps on the results are not yet well defined. We aimed to determine optimal steps for efficient extraction of… read more here.
Keywords: analytical analytical; optimization pre; analytical steps; pre analytical ... See more keywords
Urine strontium-90 (Sr-90) manual and automated pre-analytical separation followed by liquid scintillation counting
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Radioanalytical and Nuclear Chemistry"
DOI: 10.1007/s10967-021-07759-z
Abstract: Responding to a radiological or nuclear incident may require assessing tens to hundreds of thousands of people for possible radionuclide contamination. The measurement of radioactive Sr is important because of its impact on people’s health.… read more here.
Keywords: automated pre; pre analytical; strontium manual; separation ... See more keywords
Reduction of pre-analytical errors in the clinical laboratory at the University Hospital of Korea through quality improvement activities.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical biochemistry"
DOI: 10.1016/j.clinbiochem.2019.05.016
Abstract: BACKGROUND The clinical laboratory is responsible for reporting accurate and expeditious results. However, the pre-analytical phase is directly related to the procedure of specimen collection and is mostly out of the direct control of the… read more here.
Keywords: intervention; quality improvement; pre analytical; analytical errors ... See more keywords
Multicentric study of the effect of pre-analytical variables in the quality of plasma samples stored in biobanks using different complementary proteomic methods.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2016.09.003
Abstract: Analytical proteomics has experienced exponential progress in the last decade and can be expected to lead research studies on diagnostic and therapeutic biomarkers in the near future. Because the development of this type of analysis… read more here.
Keywords: samples stored; quality; pre analytical; stored biobanks ... See more keywords
Pre-analytical processes in medical diagnostics: New regulatory requirements and standards.
Sign Up to like & getrecommendations! Published in 2019 at "New biotechnology"
DOI: 10.1016/j.nbt.2019.05.002
Abstract: In May 2017, the European In Vitro Diagnostic Regulation (IVDR) entered into force and will apply to in vitro diagnostics from May 26th, 2022. This will have a major impact on the in vitro diagnostics… read more here.
Keywords: analytical processes; processes medical; medical diagnostics; pre analytical ... See more keywords
How standardization of the pre-analytical phase of both research and diagnostic biomaterials can increase reproducibility of biomedical research and diagnostics.
Sign Up to like & getrecommendations! Published in 2019 at "New biotechnology"
DOI: 10.1016/j.nbt.2019.06.007
Abstract: Comparison of published biomedical studies shows that a large proportion are irreproducible, causing severe damage to society and creating an image of wasted investments. These observations are of course damaging to the biomedical research field,… read more here.
Keywords: biomedical research; research; pre analytical; analytical phase ... See more keywords
Comparison of pre-analytical conditions for quantification of serotonin in platelet-poor plasma
Sign Up to like & getrecommendations! Published in 2019 at "Practical Laboratory Medicine"
DOI: 10.1016/j.plabm.2019.e00136
Abstract: Background Reported concentrations of serotonin in platelet-poor plasma (PPP) in healthy subjects vary widely due to different pre-analytical procedures. Aim To examine how different pre-analytical conditions affect the measured concentration of serotonin in PPP. Method… read more here.
Keywords: serotonin platelet; pre analytical; centrifugation; poor plasma ... See more keywords
Impact of specific preclinical variables on coagulation biomarkers in cancer-associated thrombosis.
Sign Up to like & getrecommendations! Published in 2020 at "Thrombosis research"
DOI: 10.1016/s0049-3848(20)30393-5
Abstract: Coagulation biomarkers are being actively studied for their diagnostic and prognostic value in patients with venous thromboembolism and cancer, as well as in the study of pathogenic mechanisms between cancer and thrombosis. For the results… read more here.
Keywords: coagulation; biomarkers cancer; pre analytical; coagulation biomarkers ... See more keywords
Stability of the Human Plasma Proteome to Pre-Analytical Variability as Assessed by an Aptamer-Based Approach.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.9b00320
Abstract: Variable processing and storage of whole blood and/or plasma are potential confounders in biomarker development and clinical assays. The goal of the study was to investigate how pre-analytical variables impact the human plasma proteome. Whole… read more here.
Keywords: storage; plasma proteome; pre analytical; aptamer based ... See more keywords
Exploring the influence of pre-analytical variables on gene expression measurements and relative expression orderings in cancer research
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-88756-0
Abstract: Gene expression profiling is an effective method for identifying predictive and prognostic biomarkers. However, measurements are prone to uncertainty and errors due to various pre-analytical variables. Systematic evaluating effects of these variables on gene expression… read more here.
Keywords: gene expression; analytical variables; expression; gene ... See more keywords
Pre-analytical diagnostic differences despite high adherence to guidelines for gestational diabetes mellitus
Sign Up to like & getrecommendations! Published in 2024 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2024.2312152
Abstract: Abstract Regional variations in the prevalence of gestational diabetes mellitus (GDM) have been found across Denmark. The objectives of this exploratory survey were to evaluate adherence to the national guideline for screening and diagnosing GDM… read more here.
Keywords: gestational diabetes; diabetes mellitus; adherence; analytical diagnostic ... See more keywords