Dysplastic stem cell plasticity functions as a driving force for neoplastic transformation of pre-cancerous gastric mucosa.
Sign Up to like & getrecommendations! Published in 2022 at "Gastroenterology"
DOI: 10.1053/j.gastro.2022.06.021
Abstract: BACKGROUND & AIMS Dysplasia carries a high risk of cancer development, however, the cellular mechanisms for dysplasia evolution to cancer are obscure. We have previously identified two putative dysplastic stem cell (DSC) populations, CD44v6neg/CD133+/CD166+ (DP)… read more here.
Keywords: cell; cell plasticity; dysplastic stem; stem cell ... See more keywords
Epidemiology of pre-cancerous cervical lesion and risk factors among adult women in Tigray, Ethiopia
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DOI: 10.1371/journal.pone.0280191
Abstract: Background Cervical cancer is a preventable disease if treated early, but remains the second leading cause of cancer-related mortality among women in low and middle-income countries. Data on epidemiology and risk factors in these settings… read more here.
Keywords: cancerous cervical; lesion; risk; cervical lesion ... See more keywords
The antigen processing-associated transporter gene polymorphism: Role on gene and protein expression in HPV-infected pre-cancerous cervical lesion
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.979800
Abstract: Human papillomavirus (HPV) is the major pathogen for cervical lesions. The evasion mechanism of the immune response and persistence of HPV infection can be influenced by polymorphisms (SNPs) in genes associated with transporter associated with… read more here.
Keywords: tap; associated transporter; hpv; expression ... See more keywords
Clinical and Pre-Clinical Evidence of Carbonic Anhydrase IX in Pancreatic Cancer and Its High Expression in Pre-Cancerous Lesions
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DOI: 10.3390/cancers12082005
Abstract: Hypoxia is a common phenomenon that occurs in most solid tumors. Regardless of tumor origin, the evolution of a hypoxia-adapted phenotype is critical for invasive cancer development. Pancreatic ductal adenocarcinoma is also characterized by hypoxia,… read more here.
Keywords: carbonic anhydrase; pancreatic cancer; pre cancerous; expression ... See more keywords
Inhibiting the Priming for Cancer in Li-Fraumeni Syndrome
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DOI: 10.3390/cancers14071621
Abstract: Simple Summary Li-Fraumeni Syndrome (LFS) is a rare cancer pre-disposition syndrome associated with a germline mutation in the TP53 tumour suppressor gene. People with LFS have a 90% chance of suffering one or more cancers… read more here.
Keywords: cancerous niche; cancer; pre cancerous; fraumeni syndrome ... See more keywords
Diagnosis of Cervical Cancer and Pre-Cancerous Lesions by Artificial Intelligence: A Systematic Review
Sign Up to like & getrecommendations! Published in 2022 at "Diagnostics"
DOI: 10.3390/diagnostics12112771
Abstract: Objective: The likelihood of timely treatment for cervical cancer increases with timely detection of abnormal cervical cells. Automated methods of detecting abnormal cervical cells were established because manual identification requires skilled pathologists and is time… read more here.
Keywords: cervical cancer; diagnosis cervical; cancer pre; review ... See more keywords