Delivering hands‐on pre‐clinical orthodontic education in the remote age
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Dental Education"
DOI: 10.1002/jdd.12320
Abstract: With the coronavirus disease 2019 (COVID-19) pandemic causing dissolution of traditional in-person instruction, education has become remote in an exceedingly short timeframe. For pre-clinical laboratory courses, this presented challenges in providing a comparable hands-on experience.… read more here.
Keywords: hands pre; clinical orthodontic; orthodontic education; pre clinical ... See more keywords
The current status of pre-clinical proton flash radiation and future directions.
Sign Up to like & getrecommendations! Published in 2021 at "Medical physics"
DOI: 10.1002/mp.15276
Abstract: We review the current status of proton FLASH experimental systems, including pre-clinical physical and biological results. Technological limitations on preclinical investigation of FLASH biological mechanisms and determination of clinically relevant parameters are discussed. A review… read more here.
Keywords: flash; proton flash; current status; proton ... See more keywords
Systematic review on the anxiolytic and hypnotic effects of flower extracts in in vivo pre‐clinical studies published from 2010 to 2020
Sign Up to like & getrecommendations! Published in 2023 at "Phytotherapy Research"
DOI: 10.1002/ptr.7830
Abstract: Anxiety disorders are prevalent conditions in the world population, whose standard approaches include pharmacotherapy, psychotherapy, and combinations of these interventions. Different classes of psychopharmaceuticals are recommended as the first line of drugs to treat these… read more here.
Keywords: effect; flower extracts; systematic review; pre clinical ... See more keywords
Pre-clinical models in pediatric traumatic brain injury—challenges and lessons learned
Sign Up to like & getrecommendations! Published in 2017 at "Child's Nervous System"
DOI: 10.1007/s00381-017-3474-2
Abstract: PurposeDespite the enormity of the problem and the lack of new therapies, research in the pre-clinical arena specifically using pediatric traumatic brain injury (TBI) models is limited. In this review, some of the key models… read more here.
Keywords: pre clinical; pediatric traumatic; tbi; brain injury ... See more keywords
Relationship of Porphyromonas gingivalis and Alzheimer's disease: a systematic review of pre-clinical studies.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical oral investigations"
DOI: 10.1007/s00784-020-03764-w
Abstract: OBJECTIVES This study aimed to analyze the following PICO question: Are animals infected with Porphyromonas gingivalis (P. gingivalis) or bacterial lipopolysaccharide (Pg-LPS) more affected by neurodegeneration, similar to the pathogenesis generated by Alzheimer's disease (AD), compared… read more here.
Keywords: alzheimer disease; porphyromonas gingivalis; disease; gingivalis ... See more keywords
Renal Effects of Incretin-Based Diabetes Therapies: Pre-clinical Predictions and Clinical Trial Outcomes
Sign Up to like & getrecommendations! Published in 2018 at "Current Diabetes Reports"
DOI: 10.1007/s11892-018-0991-7
Abstract: Purpose of ReviewThe purpose of this review is to correlate predictions based on pre-clinical data with outcomes from clinical trials that examine the effects of incretin-based diabetes treatments on the kidney. The incretin-based treatments include… read more here.
Keywords: incretin based; pre clinical; clinical trials; renal effects ... See more keywords
A Multi-Model Pipeline for Translational Intracerebral Haemorrhage Research
Sign Up to like & getrecommendations! Published in 2020 at "Translational Stroke Research"
DOI: 10.1007/s12975-020-00830-z
Abstract: Apart from acute and chronic blood pressure lowering, we have no specific medications to prevent intracerebral haemorrhage (ICH) or improve outcomes once bleeding has occurred. One reason for this may be related to particular limitations… read more here.
Keywords: research; pipeline; intracerebral haemorrhage; research multi ... See more keywords
A window into the brain: Tools to assess pre-clinical efficacy of biomaterials-based therapies on central nervous system disorders.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced drug delivery reviews"
DOI: 10.1016/j.addr.2019.01.012
Abstract: Therapeutic conveyance into the brain is a cardinal requirement for treatment of diverse central nervous system (CNS) disorders and associated pathophysiology. Effectual shielding of the brain by the blood-brain barrier (BBB) sieves out major proportion… read more here.
Keywords: nervous system; central nervous; delivery; pre clinical ... See more keywords
Culture of patient-derived multicellular clusters in suspended hydrogel capsules for pre-clinical personalized drug screening
Sign Up to like & getrecommendations! Published in 2022 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2022.03.020
Abstract: A personalized medication regimen provides precise treatment for an individual and can be guided by pre-clinical drug screening. The economical and high-efficiency simulation of the liver tumor microenvironment (TME) in a drug-screening model has high… read more here.
Keywords: drug; pre clinical; drug screening; patient derived ... See more keywords
Stem cells and their extracellular vesicles as natural and bioinspired carriers for the treatment of neurological disorders
Sign Up to like & getrecommendations! Published in 2021 at "Current Opinion in Colloid and Interface Science"
DOI: 10.1016/j.cocis.2021.101460
Abstract: Abstract One of the most explored strategy to cure neurological disorders is the transplantation of stem cells and of their derived products. Different stem cells, as well as their extracellular vesicles (EV), modified or not,… read more here.
Keywords: pre clinical; cells extracellular; stem cells; stem ... See more keywords
Shared and unique immune alterations in pre-clinical autoimmunity.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2019.08.006
Abstract: Progression from health to a classified autoimmune disease is an evolving process that can happen rapidly in some diseases, but usually takes years to develop. Specific immune alterations predate pathogenic autoimmunity and can be used… read more here.
Keywords: clinical autoimmunity; shared unique; pre clinical; unique immune ... See more keywords