Chronic Pharmacological Modulation of Mitochondrial Dynamics Alleviates Prediabetes-Induced Myocardial Ischemia–Reperfusion Injury by Preventing Mitochondrial Dysfunction and Programmed Apoptosis
Sign Up to like & getrecommendations! Published in 2021 at "Cardiovascular Drugs and Therapy"
DOI: 10.1007/s10557-021-07250-7
Abstract: There is an increasing body of evidence to show that impairment in mitochondrial dynamics including excessive fission and insufficient fusion has been observed in the pre-diabetic condition. In pre-diabetic rats with cardiac ischemia–reperfusion (I/R) injury,… read more here.
Keywords: reperfusion injury; mitochondrial dynamics; ischemia reperfusion; pre diabetic ... See more keywords
The effects of a [3+1] oxo-free rhenium (V) compound with uracil-derived ligands on selected parameters of glucose homeostasis in diet-induced pre-diabetic rats
Sign Up to like & getrecommendations! Published in 2020 at "Obesity Medicine"
DOI: 10.1016/j.obmed.2020.100258
Abstract: Abstract Introduction Prediabetes leads to the onset of type 2 diabetes. Management of prediabetes involves lifestyle intervention and the use of anti-hyperglycaemic drugs such as metformin. However, patients tend to become overly-dependent on the pharmacotherapy… read more here.
Keywords: rhenium compound; glucose homeostasis; rhenium; pre diabetic ... See more keywords
The cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet-induced obese pre-diabetic mice
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DOI: 10.1038/s41598-017-03292-w
Abstract: LH-21 is a triazol derivative that has been described as a low-permeant neutral CB1 antagonist, though its pharmacology is still unclear. It has been associated with anti-obesity actions in obese rats. However, its role in… read more here.
Keywords: glucose handling; obese pre; ligand reduces; cannabinoid ligand ... See more keywords
The effect of green coffee and/or endurance exercise on sperm function in pre‐diabetic mice
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DOI: 10.1111/and.14560
Abstract: This study aimed to investigate the effect of green coffee (GC), chlorogenic acid (CA) as an active ingredient of GC and exercise, alone or in a combination with exercise, on spermatogenesis and sperm function in… read more here.
Keywords: effect; pre diabetic; exercise; diabetic mice ... See more keywords
The effect of cardamom supplementation on serum lipids, glycemic indices and blood pressure in overweight and obese pre-diabetic women: a randomized controlled trial
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Diabetes and Metabolic Disorders"
DOI: 10.1186/s40200-017-0320-8
Abstract: BackgroundSpice consumption helps the treatment of diseases due to their antioxidant and anti-inflammatory contents. Cardamom is one of this spices; therefore, this study is designed to determine the effect of cardamom supplementation on serum lipids,… read more here.
Keywords: cardamom; group; blood pressure; blood ... See more keywords
Boosting diabetes and pre-diabetes screening in rural Ghana.
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DOI: 10.12688/f1000research.18497.1
Abstract: Background: Diabetes is a growing worldwide disease with serious consequences to health and with a high financial burden. Ghana is one of the developing African countries where the prevalence of diabetes is increasing. Moreover, many… read more here.
Keywords: pre diabetic; rural ghana; ghana; diabetes pre ... See more keywords
Exercise training-attenuated insulin resistance and liver injury in elderly pre-diabetic patients correlates with NLRP3 inflammasome
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1082050
Abstract: Background Diabetes is one of the most common metabolic diseases and continues to be a leading cause of death worldwide. The NLRP3 inflammasome has been shown to exert detrimental effects on diabetic models. However, evidence… read more here.
Keywords: pre diabetic; resistance liver; nlrp3 inflammasome; insulin resistance ... See more keywords
Identification of Pre-Diabetic Biomarkers in the Progression of Diabetes Mellitus
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DOI: 10.3390/biomedicines10010072
Abstract: Type 2 diabetes mellitus (T2DM) is a major global health issue. The development of T2DM is gradual and preceded by the pre-diabetes mellitus (pre-DM) stage, which often remains undiagnosed. This study aimed to identify novel… read more here.
Keywords: pre; pre diabetic; diabetic biomarkers; diabetes mellitus ... See more keywords
Peripheral Neuropathy Presents Similar Symptoms and Pathological Changes in Both High-Fat Diet and Pharmacologically Induced Pre- and Diabetic Mouse Models
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DOI: 10.3390/life11111267
Abstract: The objective of the study was to compare the effects of experimentally induced type 1 or type 2 diabetes (T1D or T2D) on the functional, structural and biochemical properties of mouse peripheral nerves. Eight-week-old C57BL/6… read more here.
Keywords: fat diet; peripheral neuropathy; pre diabetic; high fat ... See more keywords
Nonsurgical periodontal-therapy improves glycosylated hemoglobin levels in pre-diabetic patients with chronic periodontitis
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DOI: 10.4239/wjd.v8.i5.213
Abstract: AIM To evaluate the effect of nonsurgical periodontal therapy on glycosylated haemoglobin levels in pre-diabetic patients with chronic periodontitis (CHP). METHODS Sixty pre-diabetic patients with CHP were selected and equally allocated to case and control… read more here.
Keywords: periodontal therapy; group; case; diabetic patients ... See more keywords