Personalising cardiovascular network models in pregnancy: A two-tiered parameter estimation approach.
Sign Up to like & getrecommendations! Published in 2019 at "International journal for numerical methods in biomedical engineering"
DOI: 10.1002/cnm.3267
Abstract: Uterine artery Doppler waveforms are often studied to determine whether a patient is at risk of developing pathologies such as pre-eclampsia. Many uterine waveform indices have been developed, which attempt to relate characteristics of the… read more here.
Keywords: parameter estimation; pre eclampsia; model; arterial stiffness ... See more keywords
The long noncoding RNA uc.294 is upregulated in early‐onset pre‐eclampsia and inhibits proliferation, invasion of trophoblast cells (HTR‐8/SVneo)
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27916
Abstract: Recently, a large number of long noncoding RNAs (lncRNAs) have been reported in human diseases that are evolutionarily conserved and are likely to play a role in many biological events including pre‐eclampsia. In our previous… read more here.
Keywords: pre eclampsia; onset pre; early onset; proliferation invasion ... See more keywords
Elevated cell‐free fetal DNA contributes to placental inflammation and antiangiogenesis via AIM2 and IFI16 during pre‐eclampsia
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29766
Abstract: Accumulated evidence has shown that pre‐eclampsia (PE) is related to both maternal and utero‐placental antiangiogenesis and inflammation. Remarkably, an elevated cell‐free fetal DNA (cffDNA) level has been found in maternal circulation; however, it remains unclear… read more here.
Keywords: elevated cell; aim2 ifi16; free fetal; dna ... See more keywords
Could circRNA be a new biomarker for pre‐eclampsia?
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23262
Abstract: Pre‐eclampsia is a devastating complication of pregnancy which is characterized by hypertension and proteinuria in pregnant women. Pre‐eclampsia is important as it is the leading cause of death. Moreover, untreated pre‐eclampsia might lead to other… read more here.
Keywords: could circrna; biomarker; circrna new; pre eclampsia ... See more keywords
The association between GSTP1 polymorphism and pre-eclampsia risk: a system review and meta-analysis
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-019-05411-6
Abstract: Purpose Oxidative stress is thought to play an important role in the pathophysiology of pre-eclampsia. Polymorphism of Glutathione S-transferase P1 (GSTP1) protect cells against the cytotoxic effects of reactive compounds. Published data on the association… read more here.
Keywords: pre eclampsia; eclampsia risk; pre; gstp1 polymorphism ... See more keywords
Changes in trends over time for the specific contribution of different risk factors for pre-eclampsia
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-020-05693-1
Abstract: The prevalence of risk factors for pre-eclampsia has changed over time; however, little is known regarding how these changes have altered the specific contribution of each risk factor. We aim to identify trends in the… read more here.
Keywords: risk; time; risk factors; pre eclampsia ... See more keywords
Interleukin-23 receptor (IL-23R) gene polymorphisms and haplotypes associated with the risk of preeclampsia: evidence from cross-sectional and in silico studies
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-019-01479-w
Abstract: PurposePre-eclampsia is a relatively common pregnancy disorder. Serum concentrations of certain pro-inflammatory molecules and cytokines like interleukin-23 may affect the pathogenesis of pre-eclampsia. The interleukin-23 receptor (IL-23R) gene plays an important role in the progression… read more here.
Keywords: pre eclampsia; risk; 23r gene;
Treatment with metformin prevents pre-eclampsia by suppressing migration of trophoblast cells via modulating the signaling pathway of UCA1/miR-204/MMP-9.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.09.099
Abstract: Metformin has been reported to be involved in the pathogenesis of PE (pre-eclampsia). This study aims to investigate the molecular mechanism of how UCA1 interferes with MMP9 expression under the influence of metformin, which contributes… read more here.
Keywords: uca1 mir; metformin; pre eclampsia; migration ... See more keywords
Cost effectiveness of medical devices to diagnose pre-eclampsia in low-resource settings.
Sign Up to like & getrecommendations! Published in 2017 at "Development engineering"
DOI: 10.1016/j.deveng.2017.06.002
Abstract: Background Maternal mortality remains a major health challenge facing developing countries, with pre-eclampsia accounting for up to 17 percent of maternal deaths. Diagnosis requires skilled health providers and devices that are appropriate for low-resource settings.… read more here.
Keywords: cost; resource settings; pre eclampsia; low resource ... See more keywords
Evaluation of MicroRNA-210 and Protein tyrosine phosphatase, non-receptor type 2 in Pre-eclampsia.
Sign Up to like & getrecommendations! Published in 2017 at "Gene"
DOI: 10.1016/j.gene.2016.10.014
Abstract: BACKGROUND The precise origin of Pre-eclampsia (PE) remains elusive. Multiple pieces of evidence support the existence of hypoxia in PE. MiRNA-210 (miR-210), which is induced by Hypoxia-Inducible Factor-1α (HIF-1α) during hypoxia, is one of the… read more here.
Keywords: ptpn2; tyrosine phosphatase; protein tyrosine; pre eclampsia ... See more keywords
Pre-eclampsia through the eyes of the obstetrician and anesthesiologist.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of obstetric anesthesia"
DOI: 10.1016/j.ijoa.2019.04.002
Abstract: Due to the high risk of morbidity and mortality from unrecognized and untreated pre-eclampsia, clinicians should have a high index of suspicion to evaluate, treat and monitor patients presenting with signs concerning for pre-eclampsia. Early… read more here.
Keywords: pre; pre eclampsia; eyes obstetrician; eclampsia eyes ... See more keywords