Plasmodium vivax pre-erythrocytic vaccines.
Sign Up to like & getrecommendations! Published in 2021 at "Parasitology international"
DOI: 10.1016/j.parint.2021.102411
Abstract: An estimated 229 million cases of malaria occurred worldwide in 2019. Both, Plasmodium falciparum and P. vivax are responsible for most of the malaria disease burden in the world. Despite difficulties in obtaining an accurate… read more here.
Keywords: vivax pre; vivax; plasmodium vivax; clinical trials ... See more keywords
Towards functional antibody-based vaccines to prevent pre-erythrocytic malaria infection
Sign Up to like & getrecommendations! Published in 2017 at "Expert Review of Vaccines"
DOI: 10.1080/14760584.2017.1295853
Abstract: ABSTRACT Introduction: An effective malaria vaccine would be considered a milestone of modern medicine, yet has so far eluded research and development efforts. This can be attributed to the extreme complexity of the malaria parasites,… read more here.
Keywords: antibody based; infection; malaria infection; vaccine ... See more keywords
Prospects for Malaria Vaccines: Pre-Erythrocytic Stages, Blood Stages, and Transmission-Blocking Stages
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DOI: 10.1155/2019/9751471
Abstract: Malaria is a disease of public health importance in many parts of the world. Currently, there is no effective way to eradicate malaria, so developing safe, efficient, and cost-effective vaccines against this disease remains an… read more here.
Keywords: erythrocytic stages; pre erythrocytic; malaria vaccines; transmission blocking ... See more keywords
Functional antibodies against Plasmodium falciparum sporozoites are associated with a longer time to qPCR-detected infection among schoolchildren in Burkina Faso
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DOI: 10.12688/wellcomeopenres.14932.2
Abstract: Background: Individuals living in malaria-endemic regions develop immunity against severe malaria, but it is unclear whether immunity against pre-erythrocytic stages that blocks initiation of blood-stage infection after parasite inoculation develops following continuous natural exposure. Methods:… read more here.
Keywords: infection; inhibition; time; blood stage ... See more keywords
Profiling Humoral Immune Response Against Pre-Erythrocytic and Erythrocytic Antigens of Malaria Parasites Among Neotropical Primates in the Brazilian Atlantic Forest
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DOI: 10.3389/fcimb.2021.678996
Abstract: Human malaria due to zoonotic transmission has been recorded in the Atlantic Forest, an extra-Amazonian area in Brazil, which are a challenge for malaria control. Naturally acquired humoral immune response against pre-erythrocytic and erythrocytic antigens… read more here.
Keywords: atlantic forest; erythrocytic antigens; immune response; pre erythrocytic ... See more keywords
Pre-Erythrocytic Vaccines against Malaria
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DOI: 10.3390/vaccines8030400
Abstract: Malaria, caused by the protozoan Plasmodium, is a devastating disease with over 200 million new cases reported globally every year. Although immunization is arguably the best strategy to eliminate malaria, despite decades of research in… read more here.
Keywords: erythrocytic vaccines; vaccines malaria; pre erythrocytic;
Synergy in anti-malarial pre-erythrocytic and transmission-blocking antibodies is achieved by reducing parasite density
Sign Up to like & getrecommendations! Published in 2018 at "eLife"
DOI: 10.7554/elife.35213
Abstract: Anti-malarial pre-erythrocytic vaccines (PEV) target transmission by inhibiting human infection but are currently partially protective. It has been posited, but never demonstrated, that co-administering transmission-blocking vaccines (TBV) would enhance malaria control. We hypothesized a mechanism… read more here.
Keywords: transmission; anti malarial; transmission blocking; parasite density ... See more keywords