Colorectal Cancer Patient‐Derived 2D and 3D Models Efficiently Recapitulate Inter‐ and Intratumoral Heterogeneity
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202201539
Abstract: Pre‐existing drug resistance and tumorigenicity of cancer cells are highly correlated with therapeutic failure and tumor growth. However, current cancer models are limited in their application to the study of intratumor functional heterogeneity in personalized… read more here.
Keywords: cancer; pre existing; existing drug; colorectal cancer ... See more keywords
Antigen‐Targeting Inserted Nanomicelles Guide Pre‐Existing Immunity to Kill Head and Neck Cancer
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202410629
Abstract: A significant challenge in cancer therapy is the identification of suitable targets that are specifically and uniformly expressed across heterogeneous tumors. The efficacy of pre‐existing antiviral immunity in tumor treatment is limited by the absence… read more here.
Keywords: cancer; immunity; head neck; antigen ... See more keywords
Atrial fibrillation detected before or after stroke: role of anticoagulation.
Sign Up to like & getrecommendations! Published in 2023 at "Annals of neurology"
DOI: 10.1002/ana.26654
Abstract: BACKGROUND Atrial fibrillation (AF) known before ischemic stroke (KAF) has been postulated to be an independent category with a recurrence risk higher than that of AF detected after stroke (AFDAS). However, it is unknown whether… read more here.
Keywords: pre existing; anticoagulation; existing anticoagulation; recurrence ... See more keywords
Impact of pre‐existing interstitial lung abnormal shadow on lung injury development and severity in patients of non‐small cell lung cancer treated with osimertinib
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DOI: 10.1002/cam4.4750
Abstract: First‐generation epidermal growth factor receptor‐tyrosine kinase inhibitor (EGFR‐TKI) sometimes causes lung injury, thereby affecting survival. Although pre‐existing interstitial lung abnormal shadow (pre‐ILS) increases the risk of lung injury by EGFR‐TKIs, its impact on osimertinib, a… read more here.
Keywords: lung; existing interstitial; pre existing; lung injury ... See more keywords
Outcomes of coronavirus disease‐2019 among veterans with pre‐existing diagnosis of heart failure
Sign Up to like & getrecommendations! Published in 2021 at "ESC Heart Failure"
DOI: 10.1002/ehf2.13291
Abstract: Pre‐existing cardiovascular disease in general and related risk factors have been associated with poor coronavirus disease‐2019 (COVID‐19) outcomes. However, data on outcomes of COVID‐19 among people with pre‐existing diagnosis of heart failure (HF) have not… read more here.
Keywords: coronavirus disease; pre existing; heart failure;
Comparative analysis between STANDARD‐E Covi‐FERON ELISA with pre‐existing IFN‐γ release assays and determination of the optimum cutoff value for assessment of T‐Cell response to SARS‐CoV‐2
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24882
Abstract: Interferon‐gamma (IFN‐γ) release assays (IGRAs) are useful for the assessment of the T‐cell response to severe acute respiratory syndrome‐coronavirus‐2 (SARS‐CoV‐2). We aimed to assess the performance of the newly developed IGRA ELISA test compared to… read more here.
Keywords: pre existing; ifn release; assessment cell; cell response ... See more keywords
Pre‐existing immunity to SARS‐CoV‐2 associates with strong T cell responses induced by inactivated COVID‐19 vaccines
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28642
Abstract: Individuals with a recent common cold coronavirus infection, which leads to pre‐existing immunity against SARS‐CoV‐2, displayed a less severe course of COVID‐19. However, the relationship between pre‐existing immunity against SARS‐CoV‐2 and the inactivated‐vaccine‐induced immune response… read more here.
Keywords: cell; pre existing; existing immunity; sars cov ... See more keywords
Lymphedema microsurgery reduces the rate of implant removal for patients who have pre‐existing lymphedema and total knee arthroplasty for knee osteoarthritis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.25517
Abstract: Patients with pre‐existing lymphedema who undergo total knee arthroplasty (TKA) for osteoarthritis (OA) are at high risk for periprosthetic joint infection. This complication usually requires removal of the implant. This study aimed to investigate whether… read more here.
Keywords: existing lymphedema; pre existing; total knee; knee ... See more keywords
Pre‐existing phytoplankton biomass concentrations shape coastal plankton response to fire‐generated ash leachate
Sign Up to like & getrecommendations! Published in 2025 at "Limnology and Oceanography"
DOI: 10.1002/lno.70087
Abstract: Climate‐driven warming is projected to intensify wildfires, increasing their frequency and severity globally. Wildfires are an increasingly significant source of atmospheric deposition, delivering nutrients, organic matter, and trace metals to coastal and open ocean waters.… read more here.
Keywords: ash leachate; biomass; pre existing; plankton ... See more keywords
Barriers in cancer trajectories of patients with pre-existing severe mental disorders-A systematic review.
Sign Up to like & getrecommendations! Published in 2023 at "Psycho-oncology"
DOI: 10.1002/pon.6138
Abstract: Patients with pre‐existing severe mental disorders are significantly less likely to receive guideline‐recommended cancer treatment and seems to have a significantly lower rate of cancer survival compared to patients with cancer without mental disorders. read more here.
Keywords: cancer; pre existing; existing severe; severe mental ... See more keywords
Enteral antipseudomonal fluoroquinolones for ventilator‐associated tracheobronchitis in children with pre‐existing tracheostomy
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.25816
Abstract: Pseudomonas aeruginosa is the most commonly isolated organism in tracheostomy‐dependent children with ventilator‐associated tracheobronchitis (VAT). Enteral treatment with an antipseudomonal fluoroquinolone such as ciprofloxacin or levofloxacin is sometimes employed, but supportive data are limited. The… read more here.
Keywords: associated tracheobronchitis; pre existing; children pre; enteral antipseudomonal ... See more keywords