Oral foci of infection and their relationship with hospital stay after haematopoietic cell transplantation
Sign Up to like & getrecommendations! Published in 2024 at "Supportive Care in Cancer"
DOI: 10.1007/s00520-024-08991-5
Abstract: Oral focus screening is recommended before HCT (haematopoietic cell transplantation). Acute foci are generally treated pre-HCT. However, it is unclear whether chronic foci should be treated pre-HCT. This study aimed to evaluate the association between… read more here.
Keywords: hospital; cell transplantation; haematopoietic cell; foci ... See more keywords
Measuring Patient-Reported Outcomes (PROs) in Allogeneic Hematopoietic Cell Transplant (HCT) Recipients
Sign Up to like & getrecommendations! Published in 2020 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2019.12.236
Abstract: PROs are increasingly used in HCT to capture symptoms, quality of life, and functional status. At the Cleveland Clinic, PROs are systematically collected prior to ambulatory visits and used in routine clinical care to identify… read more here.
Keywords: time; hct; post hct; pre hct ... See more keywords
Prospective Analysis of Complement Activation in Allogeneic Transplant Recipients and Correlation with Transplant Associated Thrombotic Microangiopathy (TA-TMA) and Acute Graft Versus Host Disease (aGVHD)
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-114892
Abstract: Background: Hematopoietic cell transplantation associated thrombotic microangiopathy (TA-TMA) is an increasingly recognized complication and is associated with higher non-relapse mortality in allogeneic transplant (HCT) patients. Recent studies have indicated an association between complement activation of… read more here.
Keywords: transplant; activation; tma; pre hct ... See more keywords
Time from AML diagnosis to HCT and pre-HCT FLT3 inhibition impact pre-transplant MRD and benefit from post-HCT gilteritinib
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-1058
Abstract: Aims BMT CTN 1506 (“MORPHO”) was a global phase 3 study of post-hematopoietic cell transplantation (HCT) maintenance with gilteritinib versus placebo for patients with FLT3-ITD-mutated AML in CR1. The study did not meet its primary… read more here.
Keywords: hct; post hct; pre hct; mrd ... See more keywords
Pre-HCT creatinine defines sex-specific risk for severe TMA after allogeneic transplantation: A report from the MIDAS consortium.
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-2429
Abstract: INTRODUCTION: Severe transplant-associated thrombotic microangiopathy (TMA) is a serious complication of allogeneic hematopoietic cell transplantation (HCT), which is frequently linked with acute GVHD. The association between serum biomarkers predictive of acute GVHD and TMA remains… read more here.
Keywords: severe tma; hct; pre hct; acute gvhd ... See more keywords
Sustained donor engraftment and clinical remission after hematopoietic cell transplantation for vexas syndrome, but with observed toxicities: Results from a prospective phase II clinical Trial
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-2514
Abstract: VEXAS is a recently described autoinflammatory disorder with bone marrow failure, caused by somatic mutations in UBA1. Disease is largely refractory to medical therapy leading to glucocorticoid dependence. Allogeneic hematopoietic cell transplant (HCT) can provide… read more here.
Keywords: donor engraftment; sustained donor; hct; cell ... See more keywords
Pre-HCT mosaicism increases relapse risk and lowers survival in acute lymphoblastic leukemia patients post-unrelated HCT.
Sign Up to like & getrecommendations! Published in 2021 at "Blood advances"
DOI: 10.1182/bloodadvances.2020003366
Abstract: Pre-HCT mosaicism is related to increased relapse risk and lower survival after unrelated HCT, independent of cytogenetics at diagnosis. Pre-HCT mosaicism could be a useful clinical tool to guide risk stratification in acute lymphoblastic leukemia… read more here.
Keywords: pre hct; hct mosaicism; relapse risk;
HCT related toxicities and mortality in frail recipients.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.e18534
Abstract: e18534 Background: Frailty is a state characterized by diminished physiological reserve and increased vulnerability to stress, and adversely affects outcomes in older patients with cancer. Geriatric assessments are not routinely used to screen older HCT… read more here.
Keywords: pre hct; frail recipients; frailty; mortality ... See more keywords