Abstract 426: Ongoing TCRβ VDJ rearrangement in pre-T LBL cell lines
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-426
Abstract: The prognosis of recurrent precursor T cell lymphoblastic leukemia/lymphoma (pre-T LBL) is poor, mainly due to chemotherapy resistance. The specific mechanism(s) leading to chemoresistance at relapse is still poorly understood. We previously characterized a mouse… read more here.
Keywords: cell lines; cell; pre lbl; vdj rearrangement ... See more keywords
Mice with a Unique Mutator Phenotype Allow Detection of Lymphoid Leukemia Tumor Suppressor Genes
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DOI: 10.1182/blood-2018-99-115176
Abstract: Mice that are homozygous for a hypomorphic allele of the DNA replication factor minichromosome maintenance protein 2 (designated Mcm2hypo) on a C57Bl/6 background are born viable and are healthy for the first 2 months of… read more here.
Keywords: tumor suppressor; suppressor genes; pre lbl; mice ... See more keywords