Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2020.108670
Abstract: Inflammation-dependent base deaminases promote therapeutic resistance in many malignancies. However, their roles in human pre-leukemia stem cell (pre-LSC) evolution to acute myeloid leukemia stem cells (LSCs) had not been elucidated. Comparative whole-genome and whole-transcriptome sequencing… read more here.
Keywords: evolution; human pre; stem; pre lsc ... See more keywords