Comparative Biochemical Studies of Disease-Associated Human Dicer Mutations on Processing of a Pre-microRNA and snoRNA.
Sign Up to like & getrecommendations! Published in 2023 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00687
Abstract: Dicer is an RNase III enzyme that is responsible for the maturation of small RNAs such as microRNAs. As Dicer's cleavage products play key roles in promoting cellular homeostasis through the fine-tuning of gene expression,… read more here.
Keywords: platform paz; dicer; pre microrna; mutations processing ... See more keywords
A novel method to identify pre-microRNA in various species knowledge base on various species
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biomedical Semantics"
DOI: 10.1186/s13326-017-0143-z
Abstract: BackgroundMore than 1/3 of human genes are regulated by microRNAs. The identification of microRNA (miRNA) is the precondition of discovering the regulatory mechanism of miRNA and developing the cure for genetic diseases. The traditional identification… read more here.
Keywords: various species; novel method; pre microrna; method identify ... See more keywords