MgO-incorporated porous nanofibrous scaffold promotes osteogenic differentiation of pre-osteoblasts
Sign Up to like & getrecommendations! Published in 2021 at "Materials Letters"
DOI: 10.1016/j.matlet.2021.130098
Abstract: Abstract A feasible approach to fabricate porous nanofibrous scaffolds structurally similar to native extracellular matrix was reported. Magnesium oxide (MgO) nanoparticles were incorporated into electrospun poly(lactic acid) (PLA)/gelatin membranes, which were processed into short fibers… read more here.
Keywords: osteogenic differentiation; porous nanofibrous; pre osteoblasts; scaffold ... See more keywords
MiR-27a-3p Targets GLP1R to Regulate Differentiation, Autophagy, and Release of Inflammatory Factors in Pre-Osteoblasts via the AMPK Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.783352
Abstract: Objective: Osteoporosis is caused by the dysregulation of bone homeostasis which is synergistically mediated by osteoclasts and osteoblasts. MiR-27a-3p is a key inhibitor of bone formation. Hence, unearthing the downstream target gene of miR-27a-3p is… read more here.
Keywords: differentiation autophagy; pre osteoblasts; inflammatory factors; differentiation ... See more keywords