Large conformational changes of a highly dynamic pre-protein binding domain in SecA
Sign Up to like & getrecommendations! Published in 2018 at "Communications Biology"
DOI: 10.1038/s42003-018-0133-4
Abstract: SecA is an essential molecular motor for the translocation of proteins across the membrane via the bacterial Sec secretion system. While the Sec system is found in all cells from archaea to multicellular eukaryotes, the… read more here.
Keywords: protein; binding domain; highly dynamic; conformational changes ... See more keywords
ATP-induced asymmetric pre-protein folding as a driver of protein translocation through the Sec machinery
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DOI: 10.7554/elife.41803
Abstract: Transport of proteins across membranes is a fundamental process, achieved in every cell by the ‘Sec’ translocon. In prokaryotes, SecYEG associates with the motor ATPase SecA to carry out translocation for pre-protein secretion. Previously, we… read more here.
Keywords: pre protein; translocation; atp induced; protein ... See more keywords