Sign Up to like & get
recommendations!
2
Published in 2019 at "Molecular cell"
DOI: 10.1016/j.molcel.2019.08.014
Abstract: Fibrillar centers (FCs) and dense fibrillar components (DFCs) are essential morphologically distinct sub-regions of mammalian cell nucleoli for rDNA transcription and pre-rRNA processing. Here, we report that a human nucleolus consists of several dozen FC/DFC…
read more here.
Keywords:
rrna;
pre rrna;
human nucleolus;
fibrillar components ... See more keywords
Sign Up to like & get
recommendations!
3
Published in 2022 at "Nature Communications"
DOI: 10.1038/s41467-022-28295-8
Abstract: RMRP encodes a non-coding RNA forming the core of the RNase MRP ribonucleoprotein complex. Mutations cause Cartilage Hair Hypoplasia (CHH), characterized by skeletal abnormalities and impaired T cell activation. Yeast RNase MRP cleaves a specific…
read more here.
Keywords:
rnase;
mutation;
pre rrna;
rnase mrp ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2020 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkaa1114
Abstract: Abstract Ribosome biogenesis is a fundamental process required for cell proliferation. Although evolutionally conserved, the mammalian ribosome assembly system is more complex than in yeasts. BCCIP was originally identified as a BRCA2 and p21 interacting…
read more here.
Keywords:
ribosome biogenesis;
biogenesis;
pre rrna;
bccip ... See more keywords
Sign Up to like & get
recommendations!
2
Published in 2022 at "RNA"
DOI: 10.1101/2022.03.01.482553
Abstract: In eukaryotes, the nucleolus is the site of ribosome biosynthesis, an essential process in all cells. While human ribosome assembly is largely evolutionarily conserved, many of the regulatory details underlying its control and function have…
read more here.
Keywords:
rrna transcription;
transcription;
pebow complex;
pre ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2020 at "Cell Proliferation"
DOI: 10.1111/cpr.12769
Abstract: M‐phase phosphoprotein 6 (MPP6) is important for 5.8S pre‐rRNA maturation in somatic cells and was screened as a female fertility factor. However, whether MPP6 functions in oocyte meiosis and fertility is not yet known. We…
read more here.
Keywords:
pre rrna;
female fertility;
phase phosphoprotein;
factor ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-110663
Abstract: Diamond-Blackfan anemia (DBA) is a rare congenital erythroblastopenia associated with haploinsufficiency of more than 15 ribosomal protein genes. We identified in the French registry a DBA patient exhibiting a large heterozygous deletion in ribosomal protein…
read more here.
Keywords:
pre rrna;
diamond blackfan;
rpsa;
blackfan anemia ... See more keywords