Reconstitution of the human tRNA splicing endonuclease complex: insight into the regulation of pre-tRNA cleavage.
Sign Up to like & getrecommendations! Published in 2020 at "Nucleic acids research"
DOI: 10.1093/nar/gkaa438
Abstract: The splicing of tRNA introns is a critical step in pre-tRNA maturation. In archaea and eukaryotes, tRNA intron removal is catalyzed by the tRNA splicing endonuclease (TSEN) complex. Eukaryotic TSEN is comprised of four core… read more here.
Keywords: splicing endonuclease; pre trna; trna splicing; trna ... See more keywords
Structural insight into precursor tRNA processing by yeast ribonuclease P
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DOI: 10.1126/science.aat6678
Abstract: Structures of eukaryotic ribonuclease P Ribonuclease P (RNase P) is a ribozyme that processes transfer RNA (tRNA) precursors and is found in all three kingdoms of life. Now, Lan et al. report the structures of… read more here.
Keywords: protein; pre trna; rnase; rna ... See more keywords
TRUE Gene Silencing
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DOI: 10.3390/ijms23105387
Abstract: TRUE gene silencing is an RNA-mediated gene expression control technology and is termed after tRNase ZL-utilizing efficacious gene silencing. In this review, I overview the potentiality of small guide RNA (sgRNA) for TRUE gene silencing… read more here.
Keywords: true gene; gene silencing; pre trna; trnase ... See more keywords