Controlling Preanalytical Process in High-Coverage Quantitative Metabolomics: Spot-Sample Collection for Mouse Urine and Fecal Metabolome Profiling.
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DOI: 10.1021/acs.analchem.9b00310
Abstract: Compared to conventional MS and NMR techniques, high-performance chemical isotope labeling (CIL) LC-MS provides accurate relative quantification of many more metabolites in biological samples. However, to apply this technique for urine and fecal metabolomics studies… read more here.
Keywords: sample collection; spot; preanalytical process; coverage ... See more keywords