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   Articles with "preb tzinger" as a keyword



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Efferent projections of excitatory and inhibitory preBötzinger Complex neurons

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recommendations! Published in 2018 at "Journal of Comparative Neurology"

DOI: 10.1002/cne.24415

Abstract: The preBötzinger Complex (preBötC), a compact medullary region essential for generating normal breathing rhythm and pattern, is the kernel of the breathing central pattern generator (CPG). Excitatory preBötC neurons in rats project to major breathing‐related… read more here.

Keywords: excitatory inhibitory; inhibitory preb; tzinger complex; preb tzinger ... See more keywords
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Fate mapping neurons and glia derived from Dbx1‐expressing progenitors in mouse preBötzinger complex

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recommendations! Published in 2017 at "Physiological Reports"

DOI: 10.14814/phy2.13300

Abstract: The brainstem preBötzinger complex (preBötC) generates the inspiratory breathing rhythm, and its core rhythmogenic interneurons are derived from Dbx1‐expressing progenitors. To study the neural bases of breathing, tamoxifen‐inducible Cre‐driver mice and Cre‐dependent reporters are used… read more here.

Keywords: dbx1 expressing; neurons glia; expressing progenitors; expression ... See more keywords
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The Purinome and the preBötzinger Complex – A Ménage of Unexplored Mechanisms That May Modulate/Shape the Hypoxic Ventilatory Response

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recommendations! Published in 2019 at "Frontiers in Cellular Neuroscience"

DOI: 10.3389/fncel.2019.00365

Abstract: Exploration of purinergic signaling in brainstem homeostatic control processes is challenging the traditional view that the biphasic hypoxic ventilatory response, which comprises a rapid initial increase in breathing followed by a slower secondary depression, reflects… read more here.

Keywords: hypoxic ventilatory; preb tzinger; ventilatory response; tzinger complex ... See more keywords
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Prostaglandin E2 Exerts Biphasic Dose Response on the PreBötzinger Complex Respiratory-Related Rhythm

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recommendations! Published in 2022 at "Frontiers in Neural Circuits"

DOI: 10.3389/fncir.2022.826497

Abstract: Inflammation in infants can cause respiratory dysfunction and is potentially life-threatening. Prostaglandin E2 (PGE2) is released during inflammatory events and perturbs breathing behavior in vivo. Here we study the effects of PGE2 on inspiratory motor… read more here.

Keywords: period; tzinger complex; burst period; preb tzinger ... See more keywords
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Cell Type-Dependent Activation Sequence During Rhythmic Bursting in the PreBötzinger Complex in Respiratory Rhythmic Slices From Mice

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recommendations! Published in 2018 at "Frontiers in Physiology"

DOI: 10.3389/fphys.2018.01219

Abstract: Spontaneous respiratory rhythmic burst activity can be preserved in the preBötzinger Complex (preBötC) of rodent medullary transverse slices. It is known, that the activation sequence of inspiratory neurons in the preBötC stochastically varies from cycle… read more here.

Keywords: activation sequence; activation; type; preb tzinger ... See more keywords
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Putting the theory into ‘burstlet theory’ with a biophysical model of burstlets and bursts in the respiratory preBötzinger complex

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recommendations! Published in 2022 at "eLife"

DOI: 10.7554/elife.75713

Abstract: Inspiratory breathing rhythms arise from synchronized neuronal activity in a bilaterally distributed brainstem structure known as the preBötzinger complex (preBötC). In in vitro slice preparations containing the preBötC, extracellular potassium must be elevated above physiological… read more here.

Keywords: tzinger complex; motor output; burstlet theory; preb tzinger ... See more keywords