Mass Spectrometry of Intact Proteins Reveals +98 u Chemical Artifacts Following Precipitation in Acetone.
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DOI: 10.1021/acs.jproteome.6b00841
Abstract: Protein precipitation in acetone is frequently employed ahead of mass spectrometry for sample preconcentration and purification. Unfortunately, acetone is not chemically inert; mass artifacts have previously been observed on glycine-containing peptides when exposed to acetone… read more here.
Keywords: precipitation; precipitation acetone; mass spectrometry; intact proteins ... See more keywords