Precise Quantitation of PTEN by Immuno-MRM: A Tool To Resolve the Breast Cancer Biomarker Controversy.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c00975
Abstract: The tumor suppressor PTEN is the main negative regulator of PI3K/AKT/mTOR signaling and is commonly found downregulated in breast cancer (BC). Conflicting data from conventional immunoassays such as immunohistochemistry (IHC) has sparked controversy about PTEN's… read more here.
Keywords: quantitation pten; mrm; biomarker; breast cancer ... See more keywords
Precise quantitation and sensitive detection of copy number within genetic variations using ligation-mediated droplet digital PCR in plasma
Sign Up to like & getrecommendations! Published in 2019 at "Analytical Methods"
DOI: 10.1039/c9ay02121c
Abstract: The analysis of cancer-associated genetic copy number variations (CNVs) has been employed for cancer diagnostics, treatment, and prognostic assessments. read more here.
Keywords: copy number; copy; quantitation sensitive; sensitive detection ... See more keywords