New clinical trial designs in the era of precision medicine
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12465
Abstract: Cancer treatment has made significant strides towards the promise of personalized medicine. Recent scientific advances have shown that there are numerous genetic deregulations that are common in multiple cancer types, raising the possibility of developing… read more here.
Keywords: medicine; drug development; trial designs; oncology ... See more keywords
Precision N-glycoproteomics reveals elevated LacdiNAc as a novel signature of intrahepatic cholangiocarcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular oncology"
DOI: 10.1002/1878-0261.13147
Abstract: Primary liver cancer, mainly comprising hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC), remains a major global health problem. Although ICC is clinically different from HCC, their molecular differences are still largely unclear. In this study,… read more here.
Keywords: precision; hcc; icc hcc; intrahepatic cholangiocarcinoma ... See more keywords
Nanofiber Aerogels with Precision Macrochannels and LL‐37‐Mimic Peptides Synergistically Promote Diabetic Wound Healing
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202206936
Abstract: Fast healing of diabetic wounds remains a major clinical challenge. Herein, this study reports a strategy to combine nanofiber aerogels containing precision macrochannels and the LL‐37‐mimic peptide W379 for rapid diabetic wound healing. Nanofiber aerogels… read more here.
Keywords: precision macrochannels; nanofiber aerogels; macrochannels mimic; diabetic wound ... See more keywords
Precision Imprinted Nanostructural Wood.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced materials"
DOI: 10.1002/adma.201903270
Abstract: Wood is a ubiquitous material, widely used in human society, that features naturally abundant, aligned longitudinal cells (e.g., tracheids in softwood and fibers/vessels in hardwood) with diameters of ≈50-1000 µm. Here, the realization of, fine… read more here.
Keywords: wood; nanostructural wood; imprinted nanostructural; surface ... See more keywords
Cancer Treatment: Integrating Artificial Intelligence and Nanotechnology for Precision Cancer Medicine (Adv. Mater. 13/2020)
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Materials"
DOI: 10.1002/adma.202070100
Abstract: Artificial intelligence (AI) and nanotechnology are instrumental in realizing the goal of precision medicine—tailoring the best treatment for each cancer patient. Recent conversion between these fields is enabling better patient data acquisition and improved design… read more here.
Keywords: cancer; precision; intelligence nanotechnology; medicine ... See more keywords
Optothermally Programmable Liquids with Spatiotemporal Precision and Functional Complexity
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202205563
Abstract: Due to the intrinsic lack of spatial order and self‐supported shape, liquids are often incompatible with precision manufacturing/processing and are potentially limited for advanced functionality. Herein, an optothermal strategy is developed to fully command phase‐separated… read more here.
Keywords: optothermally programmable; liquids spatiotemporal; programmable liquids; functional complexity ... See more keywords
Magnetic–Acoustic Sequentially Actuated CAR T Cell Microrobots for Precision Navigation and In Situ Antitumor Immunoactivation
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202211509
Abstract: Despite its clinical success, chimeric antigen receptor T (CAR T)‐cell immunotherapy remains limited in solid tumors, owing to the harsh physical barriers and immunosuppressive microenvironment. Here a CAR‐T‐cell‐based live microrobot (M‐CAR T) is created by… read more here.
Keywords: cell; antitumor; car; magnetic acoustic ... See more keywords
High-Precision Printing of Complex Glass Imaging Optics with Precondensed Liquid Silica Resin.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced science"
DOI: 10.1002/advs.202105595
Abstract: 3D printing of optics has gained significant attention in optical industry, but most of the research has been focused on organic polymers. In spite of recent progress in 3D printing glass, 3D printing of precision… read more here.
Keywords: liquid silica; printing; imaging applications; glass ... See more keywords
Enhancing Parameter Estimation Precision in a Dissipative Environment with Two‐Photon Driving
Sign Up to like & getrecommendations! Published in 2020 at "Annalen der Physik"
DOI: 10.1002/andp.201900387
Abstract: We investigate the frequency estimation of an optical field suffering from an unavoidable dissipative environment. Generally, dissipative noises greatly reduce the precision. Here, we find that two-photon driving can improve the measurement precision by resisting… read more here.
Keywords: photon; two photon; photon driving; precision ... See more keywords
Easy as piadcs: A low‐cost, ultra‐high‐resolution data acquisition system using a Raspberry Pi
Sign Up to like & getrecommendations! Published in 2022 at "Applications in Plant Sciences"
DOI: 10.1002/aps3.11485
Abstract: Abstract Premise High‐precision data acquisition (DAQ) is essential for developing new methods in the plant sciences. Commercial high‐resolution DAQ systems are cost prohibitive, whereas the less expensive systems that are currently available lack the resolution… read more here.
Keywords: system; data acquisition; ultra high; high resolution ... See more keywords
Hope and challenge: Precision medicine in bladder cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.1979
Abstract: Bladder cancer (BC) is a complex disease and could be classified into nonmuscle‐invasive BC (NMIBC) or muscle‐invasive BC (MIBC) subtypes according to the distinct genetic background and clinical prognosis. Until now, the golden standard and… read more here.
Keywords: medicine; bladder cancer; precision; precision medicine ... See more keywords