Precision medicine‐based therapies in advanced colorectal cancer: The University of California San Diego Molecular Tumor Board experience
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13202
Abstract: Treatment for advanced colorectal cancer is often limited by complex molecular profiles, which promote resistance to systemic agents and targeted monotherapies. Recent studies suggest that a personalized, combinatorial approach of matching drugs to tumor alterations… read more here.
Keywords: advanced colorectal; precision medicine; colorectal cancer; tumor ... See more keywords
Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine
Sign Up to like & getrecommendations! Published in 2025 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.70003
Abstract: Medical digital twins (MDTs) are virtual representations of patients that simulate the biological, physiological, and clinical processes of individuals to enable personalized medicine. With the increasing complexity of omics data, particularly multiomics, there is a… read more here.
Keywords: digital twins; enhancing interpretability; medicine; precision medicine ... See more keywords
Organoids‐On‐a‐Chip for Personalized Precision Medicine
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202401843
Abstract: The development of personalized precision medicine has become a pivotal focus in modern healthcare. Organoids‐on‐a‐Chip (OoCs), a groundbreaking fusion of organoid culture and microfluidic chip technology, has emerged as a promising approach to advancing patient‐specific… read more here.
Keywords: precision medicine; medicine; personalized precision; organoids chip ... See more keywords
Sensing, Imaging, and Therapeutic Strategies Endowing by Conjugate Polymers for Precision Medicine
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Materials"
DOI: 10.1002/adma.202310032
Abstract: Conjugated polymers (CPs) have promising applications in biomedical fields, such as disease monitoring, real‐time imaging diagnosis, and disease treatment. As a promising luminescent material with tunable emission, high brightness and excellent stability, CPs are widely… read more here.
Keywords: imaging therapeutic; therapeutic strategies; cps; medicine ... See more keywords
Rapid Fabrication of Self-Propelled and Steerable Magnetic Microcatheters for Precision Medicine.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced materials"
DOI: 10.1002/adma.202506591
Abstract: Minimally invasive therapies demand precise navigation through complex and delicate anatomical pathways, requiring medical tools that are small, flexible, and highly maneuverable. Here, a high-yield fabrication method for the production of magnetic tubular microrobots, tethered… read more here.
Keywords: rapid fabrication; navigation; medicine; precision medicine ... See more keywords
Modularized Extracellular Vesicles: The Dawn of Prospective Personalized and Precision Medicine
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Science"
DOI: 10.1002/advs.201700449
Abstract: Abstract Extracellular vesicles (EVs) are ubiquitous nanosized membrane vesicles consisting of a lipid bilayer enclosing proteins and nucleic acids, which are active in intercellular communications. EVs are increasingly seen as a vital component of many… read more here.
Keywords: extracellular vesicles; medicine; precision medicine; personalized precision ... See more keywords
“Precision Medicine” and the Failed Search for Binary Brain Sex Differences to Address Gender Behavioral Health Disparities
Sign Up to like & getrecommendations! Published in 2025 at "American Journal of Human Biology"
DOI: 10.1002/ajhb.70041
Abstract: Human brain imaging took off in the 1980s and has since flooded the zone in the analysis of gender differences in behavior and mental health. Couched in the aims of “precision medicine,” the vast majority… read more here.
Keywords: brain; sex differences; medicine; precision medicine ... See more keywords
Hope and challenge: Precision medicine in bladder cancer
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.1979
Abstract: Bladder cancer (BC) is a complex disease and could be classified into nonmuscle‐invasive BC (NMIBC) or muscle‐invasive BC (MIBC) subtypes according to the distinct genetic background and clinical prognosis. Until now, the golden standard and… read more here.
Keywords: medicine; bladder cancer; precision; precision medicine ... See more keywords
Application of organoid culture from HPV18‐positive small cell carcinoma of the uterine cervix for precision medicine
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5588
Abstract: Small cell carcinoma of the uterine cervix (SCCC) is a rare and highly malignant human papillomavirus (HPV)‐associated cancer in which human genes related to the integration site can serve as a target for precision medicine.… read more here.
Keywords: cell carcinoma; precision medicine; small cell; carcinoma uterine ... See more keywords
Implementation of precision medicine in clinical trials in thoracic oncology: Which are the hurdles?
Sign Up to like & getrecommendations! Published in 2017 at "Cancer"
DOI: 10.1002/cncr.31055
Abstract: The adequate histologic subtyping of non–small cell lung cancer (NSCLC) secondary to the clinical need of tailoring systemic therapies has been challenged by small sample sizes of primary or metastatic lung tumors obtained through fineneedle… read more here.
Keywords: medicine; precision medicine; biomarker; disease ... See more keywords
Metagenomic Profiling of Gut Microbiota in Kidney Precision Medicine Project Participants With CKD and AKI
Sign Up to like & getrecommendations! Published in 2025 at "Comprehensive Physiology"
DOI: 10.1002/cph4.70058
Abstract: The gut microbiome plays an important role in human health and disease. Kidney Precision Medicine Project (KPMP) is a well‐phenotyped, kidney biopsy‐proven cohort of AKI and CKD patients. Comprehensive profiling of gut microbiota can uncover… read more here.
Keywords: medicine project; profiling gut; gut microbiota; kidney precision ... See more keywords