Unconstrained Precision Mitochondrial Genome Editing with αDdCBEs
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DOI: 10.1089/hum.2024.073
Abstract: DddA-derived cytosine base editors (DdCBEs) enable the targeted introduction of C•G-to-T•A conversions in mitochondrial DNA (mtDNA). DdCBEs work in pairs, with each arm composed of a transcription activator-like effector (TALE), a split double-stranded DNA deaminase… read more here.
Keywords: tale; mtdna; precision mitochondrial; mitochondrial genome ... See more keywords