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Published in 2023 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2023.2173064
Abstract: ABSTRACT Introduction The treatment landscape of biliary cancers is rapidly changing. Inhibitors against the actionable targets FGFR and IDH1 are now being included in the treatment guidelines of multiple countries for patients with advanced cholangiocarcinoma.…
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Keywords:
precision therapies;
clinical trials;
novel precision;
therapies cholangiocarcinoma ... See more keywords
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Published in 2020 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1009100
Abstract: Elucidating the functional consequence of molecular defects underlying genetic diseases enables appropriate design of therapeutic options. Treatment of cystic fibrosis (CF) is an exemplar of this paradigm as the development of CFTR modulator therapies has…
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Keywords:
protein;
precision therapies;
cftr;
intronic variants ... See more keywords
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Published in 2021 at "Journal of Personalized Medicine"
DOI: 10.3390/jpm11121353
Abstract: Cystic fibrosis (CF) is a devastating genetic infant-onset disease [...].
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Keywords:
cystic fibrosis;
precision therapies;
determined genetic;
need precision ... See more keywords