Articles with "preclinical pharmacokinetics" as a keyword



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Preclinical pharmacokinetics and ADME characterization of a novel anticancer chalcone, cardamonin.

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Published in 2017 at "Drug testing and analysis"

DOI: 10.1002/dta.2128

Abstract: Cardamonin (CRD), a chalconoid obtained from several medicinal plants of Zingiberaceae family, had shown promising potential in cancer prevention and therapy. For further development and better pharmacological elucidation, we performed a series of in vitro… read more here.

Keywords: cardamonin; characterization novel; preclinical pharmacokinetics; pharmacokinetics adme ... See more keywords
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Preclinical pharmacokinetics of benznidazole‐loaded interpolyelectrolyte complex‐based delivery systems

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Published in 2018 at "European Journal of Pharmaceutical Sciences"

DOI: 10.1016/j.ejps.2018.07.005

Abstract: &NA; Benznidazole (BZ), first‐line drug for Chagas treatment, is available as immediate‐release tablets. High frequency of administration, long‐term therapy, and side effects of BZ conspire against treatment adherence, and negatively impact in therapeutic success. We… read more here.

Keywords: treatment; preclinical pharmacokinetics; loaded interpolyelectrolyte; benznidazole ... See more keywords