Epigenomic preconditioning of peripheral monocytes determines their transcriptional response to the tumor microenvironment
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DOI: 10.1186/s13073-025-01511-y
Abstract: Monocytes are recruited to tumors and undergo transcriptional reprogramming resulting in tumor-promoting functions. Epigenomic features, such as post-translational modification of histones and chromatin accessibility, are key determinants of transcription factor binding and thereby play an… read more here.
Keywords: peripheral monocytes; response tumor; preconditioning peripheral; tumor microenvironment ... See more keywords