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Published in 2018 at "Journal of The American Society for Mass Spectrometry"
DOI: 10.1007/s13361-017-1856-z
Abstract: AbstractNeuropeptides are important signaling molecules used by nervous systems to mediate and fine-tune neuronal communication. They can function as neurotransmitters or neuromodulators in neural circuits, or they can be released as neurohormones to target distant…
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Keywords:
spectrometric resource;
mass spectrometric;
resource;
precursor proteins ... See more keywords
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Published in 2019 at "Nature"
DOI: 10.1038/s41586-019-1227-y
Abstract: Mitochondrial biogenesis and functions depend on the import of precursor proteins via the ‘translocase of the outer membrane’ (TOM complex). Defects in protein import lead to an accumulation of mitochondrial precursor proteins that induces a…
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Keywords:
precursor proteins;
associated degradation;
translocation associated;
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Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.806426
Abstract: The vast majority of mitochondrial proteins are encoded in the nuclear genome and synthesized on cytosolic ribosomes as precursor proteins with specific mitochondrial targeting signals. Mitochondrial targeting signals are very diverse, however, about 70% of…
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Keywords:
tim23 complexes;
proteins across;
across two;
precursor proteins ... See more keywords