Not only metformin, but also D-allulose, alleviates metabolic disturbance and cognitive decline in prediabetic rats.
Sign Up to like & getrecommendations! Published in 2020 at "Nutritional neuroscience"
DOI: 10.1080/1028415x.2020.1840050
Abstract: BACKGROUND Prediabetes can be characterized as obesity with metabolic disturbance, leading to cognitive decline and brain pathologies. D-allulose administration in obese animals decreased metabolic disturbance. However, the comparative effects of D-allulose and metformin on cognition… read more here.
Keywords: prediabetic rats; cognitive decline; metabolic disturbance; brain ... See more keywords
PCSK9 inhibitor and atorvastatin reduce cardiac impairment in ovariectomized prediabetic rats via improved mitochondrial function and Ca2+ regulation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15556
Abstract: Post‐menopausal women have a higher risk of developing cardiometabolic dysfunction. Atorvastatin attenuates dyslipidaemia and cardiac dysfunction but it can have undesirable effects including increased risk of diabetes and myalgia. Currently, the proprotein convertase subtilisin/kexin type… read more here.
Keywords: pcsk9 inhibitor; inhibitor; prediabetic rats; function ... See more keywords