Models Used to Predict Chemical Bioaccumulation in Fish from in Vitro Biotransformation Rates Require Accurate Estimates of Blood–Water Partitioning and Chemical Volume of Distribution
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DOI: 10.1002/etc.5503
Abstract: Methods for extrapolating measured in vitro intrinsic clearance to a whole‐body biotransformation rate constant (kB) have been developed to support modeled bioaccumulation assessments for fish. The inclusion of extrapolated kB values into existing bioaccumulation models… read more here.
Keywords: predict chemical; volume distribution; biotransformation; used predict ... See more keywords