iTRAQ‐based quantitative proteomics reveals biomarkers/pathways in psoriasis that can predict the efficacy of methotrexate
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.18292
Abstract: Methotrexate (MTX) is the first‐line medicine to treat psoriasis. So far, there has been less research on protein biomarkers to predict its efficacy by the proteomic technique. read more here.
Keywords: itraq based; methotrexate; based quantitative; quantitative proteomics ... See more keywords
Genetic polymorphisms of CCL5 and CCR5 to predict efficacy of cetuximab-based treatment in metastatic colorectal cancer patients depending on primary tumor location.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.3594
Abstract: 3594Background: EGFR signaling blockade increases CCL5 expression, which attracts with tumor-infiltrating leukocytes regulating either the host-derived anti-tumor immunity or tumor progression. We ... read more here.
Keywords: genetic polymorphisms; predict efficacy; polymorphisms ccl5; ccr5 predict ... See more keywords
Tumor associated macrophages to predict the efficacy of bevacizumab plus chemotherapy in patients with advanced colorectal cancer.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e15103
Abstract: e15103Background: The tumor-associated macrophage (TAM) is one of the major components of tumor microenvironment. Neuroendocrine differentiation (NED) of the tumor has been linked to poor prognosis... read more here.
Keywords: tumor associated; efficacy bevacizumab; predict efficacy; macrophages predict ... See more keywords
Mutation profiles in circulating tumor DNA (ctDNA) to predict the efficacy of sorafenib treatment in patients with advanced hepatocellular carcinoma (HCC).
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.e15648
Abstract: e15648 Background: To find biomarkers from blood samples through ctDNA and leucocyte genomic DNA sequencing to predict the efficacy of sorafenib. Methods: CtDNA and leucocyte genomic DNA were extracted from patients with advanced hepatocellular carcinoma… read more here.
Keywords: hepatocellular carcinoma; advanced hepatocellular; efficacy; predict efficacy ... See more keywords
Clinical parameters combined with radiomics features to predict the efficacy of immunotherapy for advanced non-small cell lung cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2021.39.15_suppl.e21187
Abstract: e21187 Background: Many tools have been developed to predict the efficacy of immunotherapy, such as LIPI, EPSILoN and mLIPI scores. The aim of this study was to determine the ability of to predict outcomes in… read more here.
Keywords: efficacy immunotherapy; predict efficacy; epsilon; radiomics features ... See more keywords