Genomic Signatures Predict the Immunogenicity of BRCA-Deficient Breast Cancer
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DOI: 10.1158/1078-0432.ccr-18-0468
Abstract: Purpose: Breast cancers with BRCA1/2 alterations have a relatively high mutational load, suggesting that immune checkpoint blockade may be a potential treatment option. However, the degree of immune cell infiltration varies widely, and molecular features… read more here.
Keywords: cancer; breast cancers; breast; predict immunogenicity ... See more keywords