Efficient Screening of Target‐Specific Selected Compounds in Mixtures by 19F NMR Binding Assay with Predicted 19F NMR Chemical Shifts
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DOI: 10.1002/cmdc.202200163
Abstract: Ligand‐based 19F NMR screening is a highly effective and well‐established hit‐finding approach. The high sensitivity to protein binding makes it particularly suitable for fragment screening. Different criteria can be considered for generating fluorinated fragment libraries.… read more here.
Keywords: 19f nmr; chemical shifts; nmr chemical; predicted 19f ... See more keywords