Articles with "predicting oral" as a keyword



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Predicting oral absorption for compounds outside the rule of five property space.

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Published in 2021 at "Journal of pharmaceutical sciences"

DOI: 10.1016/j.xphs.2021.01.029

Abstract: The estimation of the extent of absorption of drug candidates intended for oral drug delivery is an important selection criteria in drug discovery. The use of cell-based transwell assays examining flux across cell-monolayers (e.g. Caco-2… read more here.

Keywords: absorption; predicting oral; property space; drug ... See more keywords