Articles with "predicting regioselectivity" as a keyword



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Predicting Regioselectivity of Cytosolic Sulfotransferase Metabolism for Drugs.

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Published in 2023 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.3c00275

Abstract: Cytosolic sulfotransferases (SULTs) are a family of enzymes responsible for the sulfation of small endogenous and exogenous compounds. SULTs contribute to the conjugation phase of metabolism and share substrates with the uridine 5'-diphospho-glucuronosyltransferase (UGT) family… read more here.

Keywords: metabolism; regioselectivity; sulfotransferase metabolism; cytosolic sulfotransferase ... See more keywords