Predicting Total Drug Clearance and Volumes of Distribution Using the Machine Learning-Mediated Multimodal Method through the Imputation of Various Nonclinical Data
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DOI: 10.1021/acs.jcim.2c00318
Abstract: Pharmacokinetic research plays an important role in the development of new drugs. Accurate predictions of human pharmacokinetic parameters are essential for the success of clinical trials. Clearance (CL) and volume of distribution (Vd) are important… read more here.
Keywords: clearance; nonclinical data; predicting total; imputation ... See more keywords