Assessing next-generation sequencing-based computational methods for predicting transcriptional regulators with query gene sets
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DOI: 10.1093/bib/bbae366
Abstract: Abstract This article provides an in-depth review of computational methods for predicting transcriptional regulators (TRs) with query gene sets. Identification of TRs is of utmost importance in many biological applications, including but not limited to… read more here.
Keywords: transcriptional regulators; computational methods; methods predicting; query gene ... See more keywords
Predicting transcriptional changes induced by molecules with MiTCP
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DOI: 10.1093/bib/bbaf006
Abstract: Abstract Studying the changes in cellular transcriptional profiles induced by small molecules can significantly advance our understanding of cellular state alterations and response mechanisms under chemical perturbations, which plays a crucial role in drug discovery… read more here.
Keywords: induced molecules; transcriptional changes; molecules mitcp; gene ... See more keywords