Articles with "predictive biomarker" as a keyword



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Comments on "Malondialdehyde: A novel predictive biomarker for post-stroke depression".

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Published in 2018 at "Journal of affective disorders"

DOI: 10.1016/j.jad.2017.07.050

Abstract: In a recent work by Liu et al. (2017) appeared in this journal, malondialdehyde levels proposed as a novel biomarker. Despite of wide usage of malondialdehyde as a biomarker, there are some points from analytical… read more here.

Keywords: malondialdehyde novel; comments malondialdehyde; predictive biomarker; biomarker ... See more keywords
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P2.01-90 PD-L1 Expression as a Predictive Biomarker in Advanced Non-Small Cell Lung Cancer Patients with or without EGFR Mutation

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Published in 2018 at "Journal of Thoracic Oncology"

DOI: 10.1016/j.jtho.2018.08.1144

Abstract: Teerada Siripoon1, Pimpin Incharoen2, Narumol Trachu3, Dittapol Munthum4, Kaettipong Kamprerasart2, Thanyanan Reungwetwattana1 Division of medical Oncology, Department of Medicine Department of Pathology Ramathibodi Research Center Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. Department… read more here.

Keywords: medicine; biomarker advanced; advanced non; predictive biomarker ... See more keywords
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MT2A is an early predictive biomarker of response to chemotherapy and a potential therapeutic target in osteosarcoma

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Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-48846-2

Abstract: Osteosarcoma is the most prevalent primary bone malignancy in children and young adults. Resistance to chemotherapy remains a key challenge for effective treatment of patients with osteosarcoma. The aim of the present study was to… read more here.

Keywords: chemotherapy; response; predictive biomarker; osteosarcoma ... See more keywords
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Bayesian additive decision trees of biomarker by treatment interactions for predictive biomarker detection and subgroup identification

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Published in 2018 at "Journal of Biopharmaceutical Statistics"

DOI: 10.1080/10543406.2017.1372770

Abstract: ABSTRACT Personalized medicine, or tailored therapy, has been an active and important topic in recent medical research. Many methods have been proposed in the literature for predictive biomarker detection and subgroup identification. In this article,… read more here.

Keywords: decision; detection subgroup; predictive biomarker; treatment ... See more keywords
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A flexible approach for predictive biomarker discovery.

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Published in 2022 at "Biostatistics"

DOI: 10.1093/biostatistics/kxac029

Abstract: An endeavor central to precision medicine is predictive biomarker discovery; they define patient subpopulations which stand to benefit most, or least, from a given treatment. The identification of these biomarkers is often the byproduct of… read more here.

Keywords: biomarker discovery; treatment rule; discovery; predictive biomarker ... See more keywords
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PD-L1 Expression in TNBC: A Predictive Biomarker of Response to Neoadjuvant Chemotherapy?

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Published in 2017 at "BioMed Research International"

DOI: 10.1155/2017/1750925

Abstract: Triple negative breast cancer (TNBC) has an aggressive clinical behaviour, with a poorer prognosis compared to other subtypes. Recently, tumor-infiltrating lymphocytes (TILs) have been proposed as a predictive biomarker for a better clinical outcome and… read more here.

Keywords: chemotherapy; response; predictive biomarker; tnbc ... See more keywords
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Abstract 4517: Novel prognostic and predictive biomarker for neuroblastoma

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-4517

Abstract: Recently we showed that Retinal degeneration protein 3 (RD3) is constitutively expressed in healthy adult and fetal tissues beyond retina and, its gradient expression from high to low in ganglioneuroma, ganglioneuroblastoma and neuroblastoma (NB). Crucially,… read more here.

Keywords: rd3; loss; predictive biomarker; novel prognostic ... See more keywords
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Abstract 953: Development of a predictive biomarker signature for the highly potent SIK3 inhibitor OMX-0407

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-953

Abstract: Using the iOTarg genetic screening platform, salt-inducible kinase 3 (SIK3), a serine/threonine kinase of the AMP-activated protein kinase (AMPK) family was recently identified as a novel cell signaling modulator in cancer biology. OMX-0407, an orally… read more here.

Keywords: signature; omx 0407; predictive biomarker; tumor ... See more keywords
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Platelet-Coated Circulating Tumor Cells Are a Predictive Biomarker in Patients with Metastatic Castrate-Resistant Prostate Cancer

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Published in 2021 at "Molecular Cancer Research"

DOI: 10.1158/1541-7786.mcr-21-0383

Abstract: Metastatic castration-resistant prostate cancer (mCRPC) includes a subset of patients with particularly unfavorable prognosis characterized by combined defects in at least two of three tumor suppressor genes: PTEN, RB1, and TP53 as aggressive variant prostate… read more here.

Keywords: cancer; prostate cancer; tumor; ctcs ... See more keywords
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KMT2A/C mutations function as a potential predictive biomarker for immunotherapy in solid tumors

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Published in 2020 at "Biomarker Research"

DOI: 10.1186/s40364-020-00241-0

Abstract: Epigenetic factors play important roles in tumor immunology. Histone-lysine N-methyltransferase 2 (KMT2) family genes exert histone H3 methylation, but its role in immunotherapy remains unclear. Our study is the first to investigate the correlation between… read more here.

Keywords: potential predictive; solid tumors; predictive biomarker; biomarker ... See more keywords
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Pre-treatment hematological markers as a predictive biomarker for survival in patients with non-small cell lung cancer treated with nivolumab.

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Published in 2017 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2017.35.15_suppl.11547

Abstract: 11547Background: The absolute neutrophil count (ANC), absolute monocyte count (AMC) and neutrophil to lymphocyte ratio (NLR) are known markers of inflammation. We evaluated whether ANC, AMC and NLR... read more here.

Keywords: markers predictive; predictive biomarker; hematological markers; biomarker survival ... See more keywords