Systematic evaluation of the predictive gene expression signatures of immune checkpoint inhibitors in metastatic melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23442
Abstract: Advances in immunotherapy, including immune checkpoint inhibitors (ICIs), have transformed the standard of care for many types of cancer including melanoma. ICIs have improved the overall outcome of melanoma patients; however, a significant proportion of… read more here.
Keywords: predictive biomarkers; checkpoint inhibitors; immune checkpoint; melanoma ... See more keywords
A review of prognostic and predictive biomarkers in breast cancer
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DOI: 10.1007/s10238-021-00781-1
Abstract: Breast cancer (BC) is a common cancer all over the world that affects women. BC is one of the leading causes of cancer mortality in women, which today has decreased with the advancement of technology… read more here.
Keywords: cancer; predictive biomarkers; review prognostic; biomarkers breast ... See more keywords
Monitoring checkpoint inhibitors: predictive biomarkers in immunotherapy
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DOI: 10.1007/s11684-018-0678-0
Abstract: Immunotherapy has become the fourth cancer therapy after surgery, chemotherapy, and radiotherapy. In particular, immune checkpoint inhibitors are proved to be unprecedentedly in increasing the overall survival rates of patients with refractory cancers, such as… read more here.
Keywords: checkpoint inhibitors; biomarkers immunotherapy; monitoring checkpoint; inhibitors predictive ... See more keywords
Progress and challenges of predictive biomarkers of anti PD-1/PD-L1 immunotherapy: A systematic review.
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DOI: 10.1016/j.canlet.2017.11.014
Abstract: Despite the marked success of applications of PD-1/PD-L1 checkpoint blockades in clinical, the efficacy and responsiveness of these agents varies greatly among different tumor types and across individual patients. Therefore, establishment of predictive biomarkers for… read more here.
Keywords: anti immunotherapy; progress challenges; provide new; challenges predictive ... See more keywords
An Update on Predictive Biomarkers in Metastatic Renal Cell Carcinoma.
Sign Up to like & getrecommendations! Published in 2019 at "European urology focus"
DOI: 10.1016/j.euf.2019.04.004
Abstract: One of the major challenges of personalized oncology lies in identifying predictive biomarkers of response to therapy that are practical in the clinical setting. Although many new targeted and immune-based treatments have emerged in recent… read more here.
Keywords: cell carcinoma; renal cell; predictive biomarkers; metastatic renal ... See more keywords
Predictive biomarkers of IgA vasculitis with nephritis by metabolomic analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Seminars in arthritis and rheumatism"
DOI: 10.1016/j.semarthrit.2020.09.006
Abstract: BACKGROUND IgA vasculitis (IgAV) is the most common vasculitis of childhood. Renal involvement defines late morbidity of the disease. A better understanding of the pathophysiology of the progression to kidney disease and predictive biomarkers are… read more here.
Keywords: igav patients; predictive biomarkers; renal involvement; iga vasculitis ... See more keywords
Update on prognostic and predictive biomarkers of breast cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in diagnostic pathology"
DOI: 10.1053/j.semdp.2022.06.015
Abstract: Breast cancer represents a heterogeneous group of human cancer at both histological and molecular levels. Estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2) are the most commonly used biomarkers… read more here.
Keywords: predictive biomarkers; biomarkers breast; breast cancer; cancer ... See more keywords
Predictive biomarkers along gastric cancer pathogenetic pathways
Sign Up to like & getrecommendations! Published in 2017 at "Expert Review of Anticancer Therapy"
DOI: 10.1080/14737140.2017.1301207
Abstract: ABSTRACT Introduction: Gastric cancer is the second leading cause of cancer all over the world. Unfortunately, several gastric cancers are diagnosed in an advanced stage and chemotherapy and/or target therapies remain the only options to… read more here.
Keywords: gastric cancer; target; along gastric; cancer ... See more keywords
The evolving role of receptors as predictive biomarkers for metastatic breast cancer
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DOI: 10.1080/14737140.2019.1552138
Abstract: ABSTRACT Introduction: In breast cancer, estrogen receptor (ER) and human epidermal growth factor receptor 2 (HER2) are essential biomarkers to predict response to endocrine and anti-HER2 therapies, respectively. In metastatic breast cancer, the use of… read more here.
Keywords: evolving role; breast; breast cancer; metastatic breast ... See more keywords
Predictive biomarkers of response to immune checkpoint inhibitors in melanoma
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DOI: 10.1080/14737140.2020.1724539
Abstract: ABSTRACT Introduction: Advanced melanoma has recently been transformed by the advent of immune checkpoint inhibitors. These agents have altered the prognosis of this disease from a median survival of read more here.
Keywords: immune checkpoint; checkpoint inhibitors; biomarkers response; checkpoint ... See more keywords
Predictive biomarkers of response to immune checkpoint inhibitors in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Molecular Diagnostics"
DOI: 10.1080/14737159.2022.2049244
Abstract: ABSTRACT Introduction Hepatocellular carcinoma (HCC) is the most common primary liver cancer and fourth-leading cause of cancer death. While drug discovery to improve disease survival was historically poor, there is now evidence of significant potential… read more here.
Keywords: predictive biomarkers; hepatocellular carcinoma; checkpoint inhibitors; immune checkpoint ... See more keywords