Prospective validation of the prognostic and predictive impact of uPA/PAI-1 in early breast cancer
Sign Up to like & getrecommendations! Published in 2025 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-025-07850-z
Abstract: An emerging challenge in early breast cancer (eBC) is improving risk assessment through the use of biomarkers. Clinical guidelines have recommended urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 for risk evaluation. This study aimed… read more here.
Keywords: predictive impact; breast cancer; pai; pai status ... See more keywords
Prognostic and predictive impact of consensus molecular subtypes and CRCAssigner classifications in metastatic colorectal cancer: a translational analysis of the TRIBE2 study
Sign Up to like & getrecommendations! Published in 2021 at "ESMO Open"
DOI: 10.1016/j.esmoop.2021.100073
Abstract: Introduction The consensus molecular subtypes (CMS) demonstrated prognostic value in metastatic colorectal cancer (mCRC). Similarly, a prognostic impact was suggested for the pre-consensus CRCAssigner (CRCA) classifier in early stages. The potential predictive role of these… read more here.
Keywords: pfs pfs2; impact; predictive impact; cms ... See more keywords
Predictive impact of clinical factors on chemosensitivity in advanced high-grade serous ovarian carcinoma according to chemotherapy response score
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DOI: 10.1097/md.0000000000040487
Abstract: The use of neoadjuvant chemotherapy (NAC) as a first-line therapy for advanced high-grade serous ovarian carcinoma (HGSOC) has increased. However, several studies have reported NAC-induced platinum resistance. This study aimed to evaluate the predictive impact… read more here.
Keywords: advanced high; predictive impact; high grade; grade serous ... See more keywords
Impact of predictive impact of MGMT promoter methylation in malignant astrocytomas depends on the methylation subgroup.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.2013
Abstract: 2013 Background: O6-methylguanine DNA-methyl transferase (MGMT) status is predictive for alkylating chemotherapy in most series, but there are non-benefitting subgroups. Despite multiple attempts, MGMT has not been unambiguously established as a predictive biomarker for patients… read more here.
Keywords: mgmt; mgmt promoter; methylation; impact mgmt ... See more keywords