Identification of risk in cutaneous melanoma patients: Prognostic and predictive markers
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Surgical Oncology"
DOI: 10.1002/jso.25319
Abstract: New therapeutic modalities for melanoma promise benefit in selected individuals. Efficacy appears greater in patients with lower tumor burden, suggesting an important role for risk‐stratified surveillance. Robust predictive markers might permit optimization of agent to… read more here.
Keywords: risk; identification risk; cutaneous melanoma; predictive markers ... See more keywords
Predictive markers for efficacy of everolimus plus exemestane in patients with luminal HER2-negative metastatic breast cancer
Sign Up to like & getrecommendations! Published in 2018 at "Medical Oncology"
DOI: 10.1007/s12032-018-1112-9
Abstract: Metastatic breast cancer (MBC) is essentially incurable despite recent improvements in systemic therapies. We often encounter difficulties in choosing the most appropriate treatments, with optimal timing, for individual patients. Everolimus, one of the mTOR inhibitors,… read more here.
Keywords: plus exemestane; breast; breast cancer; predictive markers ... See more keywords
Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s Disease
Sign Up to like & getrecommendations! Published in 2017 at "Cell Stem Cell"
DOI: 10.1016/j.stem.2016.09.004
Abstract: Summary Stem cell treatments for neurodegenerative diseases are expected to reach clinical trials soon. Most of the approaches currently under development involve transplantation of immature progenitors that subsequently undergo phenotypic and functional maturation in vivo,… read more here.
Keywords: graft; parkinson disease; predictive markers; graft outcome ... See more keywords
Typing the atypical: Diagnostic issues and predictive markers in suspicious prostate lesions
Sign Up to like & getrecommendations! Published in 2017 at "Critical Reviews in Clinical Laboratory Sciences"
DOI: 10.1080/10408363.2017.1363155
Abstract: Abstract As much as 5% of prostate biopsies yield findings equivocal for malignancy even for skilled uropathologist; such “grey zone” lesions have been addressed in many ways, although the acronym ASAP (atypical small acinar proliferation)… read more here.
Keywords: prostate; typing atypical; diagnostic issues; issues predictive ... See more keywords
Prognostic and predictive markers of systemic sclerosis-interstitial lung disease in a clinical trial and long-term observational cohort.
Sign Up to like & getrecommendations! Published in 2023 at "Rheumatology"
DOI: 10.1093/rheumatology/kead234
Abstract: OBJECTIVES Explore prognostic and predictive markers of systemic sclerosis-associated interstitial lung disease (SSc-ILD) outcomes in a phase 3 trial (focuSSced) and prognostic markers in a real-world cohort (SMART). METHODS The focuSSced SSc-ILD subgroup included 68… read more here.
Keywords: disease; markers systemic; trial; cohort ... See more keywords
Early-Stage Predictive Markers of Critically Ill COVID-19 Cases.
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Emergency Care"
DOI: 10.1097/pec.0000000000002335
Abstract: To the Editors: C OVID-19 pandemic has caused devastating damages to global economy and frightening human deaths worldwide. High transmissibility and fatality of COVID-19 have been an unprecedented challenge to global health. Although more than… read more here.
Keywords: critically ill; markers critically; predictive markers; stage predictive ... See more keywords
Expert Discussion: Predictive Markers
Sign Up to like & getrecommendations! Published in 2021 at "Breast Care"
DOI: 10.1159/000519562
Abstract: a Experimental Oncology, Istituto Tumori G. Paolo II, IRCCS, Bari, Italy; b Department of Medical and Surgical Sciences and Biotechnology, University of Rome la Sapienza, Latina, Italy; c Division of Medical Senology, European Institute of… read more here.
Keywords: discussion predictive; expert discussion; predictive markers; oncology ... See more keywords
Prognostic/predictive markers in systemic therapy resistance and metastasis in breast cancer
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic Advances in Medical Oncology"
DOI: 10.1177/17588359221112698
Abstract: Breast cancer is a highly heterogeneous group of diseases posing a significant challenge in biomarker-driven research and the development of effective targeted therapies. Especially the treatment of metastatic breast cancer poses even more challenges, as… read more here.
Keywords: breast; breast cancer; resistance; predictive markers ... See more keywords
LACES and bootstraps: the hunt for prognostic and predictive markers for adjuvant therapy in NSCLC.
Sign Up to like & getrecommendations! Published in 2018 at "Translational lung cancer research"
DOI: 10.21037/tlcr.2018.09.01
Abstract: The benefit from adjuvant chemotherapy in resected non-small cell lung cancer (NSCLC) is modest with an overall survival (OS) benefit of only ~5% demonstrated in the Lung Adjuvant Cisplatin Evaluation (LACE) meta-analysis (1). read more here.
Keywords: bootstraps hunt; nsclc; hunt prognostic; prognostic predictive ... See more keywords
Pretreatment Platelet Count and Neutrophil/Lymphocyte Ratio Are Predictive Markers for Carboplatin Plus Pemetrexed Therapy-induced Thrombocytopenia
Sign Up to like & getrecommendations! Published in 2021 at "AntiCancer Research"
DOI: 10.21873/anticanres.15389
Abstract: Background/Aim: This study aimed to identify the predictive markers for carboplatin-induced severe thrombocytopenia. Patients and Methods: We conducted a retrospective cohort analysis of inpatients who received carboplatin and pemetrexed. Results: Among the 106 eligible patients,… read more here.
Keywords: platelet count; neutrophil lymphocyte; lymphocyte ratio; predictive markers ... See more keywords
Triglyceride glucose index, pediatric NAFLD fibrosis index, and triglyceride-to-high-density lipoprotein cholesterol ratio are the most predictive markers of the metabolically unhealthy phenotype in overweight/obese adolescent boys
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1124019
Abstract: Introduction The prevalence of obesity constantly increases worldwide and definitely increases the risk of premature death in early adulthood. While there is no treatment yet with proven efficacy for the metabolic clamp such as arterial… read more here.
Keywords: markers metabolically; index; metabolically unhealthy; overweight obese ... See more keywords