Biomarker Predictors for Immunotherapy Benefit in Breast: Beyond PD-L1
Sign Up to like & getrecommendations! Published in 2019 at "Current Breast Cancer Reports"
DOI: 10.1007/s12609-019-00331-5
Abstract: Immune checkpoint blockade (ICB) has changed the clinical course of multiple cancer types and durable responses have now been observed in breast cancer (BC) patients. Most data suggest that, compared to other subtypes, triple-negative BC… read more here.
Keywords: biomarker predictors; benefit breast; immunotherapy benefit; breast ... See more keywords
New predictors for immunotherapy responses sharpen our view of the tumour microenvironment
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DOI: 10.1038/d41586-019-03943-0
Abstract: Three studies reveal that the presence in tumours of two key immune components — B cells and tertiary lymphoid structures — is associated with favourable outcomes when individuals undergo immunotherapy. B cells are associated with… read more here.
Keywords: responses sharpen; new predictors; predictors immunotherapy; view tumour ... See more keywords
Predictors of immunotherapy induced immune-related adverse events
Sign Up to like & getrecommendations! Published in 2019 at "Lung cancer"
DOI: 10.1183/13993003.congress-2019.pa4665
Abstract: Background: Immune-related adverse events (IRAE) represent a challenge, potentially limiting the clinical benefits of immune check point inhibitors therapy (ICI). Aim: To evaluate the prevalence and identified potential predictive factors (PF) of IRAE in clinical… read more here.
Keywords: predictors immunotherapy; immune related; pts irae; nivolumab pts ... See more keywords
Acute Phase Proteins as Early Predictors for Immunotherapy Response in Advanced NSCLC: An Explorative Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.772076
Abstract: In the last decade, targeting the immune system became a promising therapy in advanced lung cancer stages. However, in a clinical follow-up, patient responses to immune checkpoint inhibitors widely differ. Peripheral blood is a minimally… read more here.
Keywords: predictors immunotherapy; early predictors; acute phase; phase proteins ... See more keywords