DeMAG predicts the effects of variants in clinically actionable genes by integrating structural and evolutionary epistatic features
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DOI: 10.1101/2022.06.15.496230
Abstract: Interpretation of rare genetic variants remains challenging. Here, the authors develop a supervised variant effect predictor for use in clinically actionable genes which incorporates evolutionary and structural relationships between residues and has balanced specificity and… read more here.
Keywords: demag predicts; clinically actionable; predicts effects; disease genes ... See more keywords