Nested Inversion Polymorphisms Predispose Chromosome 22q11.2 to Meiotic Rearrangements.
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DOI: 10.1016/j.ajhg.2017.09.002
Abstract: Inversion polymorphisms between low-copy repeats (LCRs) might predispose chromosomes to meiotic non-allelic homologous recombination (NAHR) events and thus lead to genomic disorders. However, for the 22q11.2 deletion syndrome (22q11.2DS), the most common genomic disorder, no… read more here.
Keywords: inversion polymorphisms; meiotic rearrangements; predispose chromosome; chromosome 22q11 ... See more keywords