Constitutive BRCA1 Promoter Hypermethylation Can Be a Predisposing Event in Isolated Early-Onset Breast Cancer
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DOI: 10.3390/cancers11010058
Abstract: Early age at onset of breast cancer (eoBC) is suggestive of an increased genetic risk. Although genetic testing is offered to all eoBC-affected women, in isolated cases the detection rate of pathogenic variants is 60%… read more here.
Keywords: methylation; brca1; onset breast; promoter ... See more keywords