A rare FGF5 candidate variant (rs112475347) for predisposition to nonsquamous, nonsmall‐cell lung cancer
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Cancer"
DOI: 10.1002/ijc.34510
Abstract: A unique approach with rare resources was used to identify candidate variants predisposing to familial nonsquamous nonsmall‐cell lung cancers (NSNSCLC). We analyzed sequence data from NSNSCLC‐affected cousin pairs belonging to high‐risk lung cancer pedigrees identified… read more here.
Keywords: lung cancer; predisposition; variant; cancer ... See more keywords
Association of histo‐blood group antigens and predisposition to gastrointestinal diseases
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28028
Abstract: Infectious gastroenteritis is a common illness afflicting people worldwide. The two most common etiological agents of viral gastroenteritis, rotavirus and norovirus are known to recognize histo‐blood group antigens (HBGAs) as attachment receptors. ABO, Lewis, and… read more here.
Keywords: predisposition; hbgas; histo blood; blood group ... See more keywords
Parents' experiences with large‐scale sequencing for genetic predisposition in pediatric renal cancer: A qualitative study
Sign Up to like & getrecommendations! Published in 2022 at "Psycho-Oncology"
DOI: 10.1002/pon.6016
Abstract: In pediatric oncology, large‐scale genetic sequencing contributes to the identification of cancer predisposition, which can facilitate surveillance and family counseling. Our qualitative study explores families' motives, knowledge, and views regarding germline genetic sequencing to improve… read more here.
Keywords: oncology; predisposition; qualitative study; large scale ... See more keywords
Dynamics of Renin, Angiotensin II, and Angiotensin (1–7) during Pregnancy and Predisposition to Hypertension-Associated Complications
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DOI: 10.1007/s10517-018-4188-5
Abstract: Changes in the levels of rennin, angiotensin II, and angiotensin (1–7) were studied during normal pregnancy. The blood was taken on gestation days 140-237 and 238-280. No significant changes in renin concentration were observed during… read more here.
Keywords: normal pregnancy; angiotensin angiotensin; pregnancy; predisposition ... See more keywords
Inherited predisposition to breast and ovarian cancer in non-Jewish populations in Israel
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DOI: 10.1007/s10549-017-4474-3
Abstract: PurposeThe contribution of genetic factors to cancer in non-Jewish populations in Israel is understudied. Yet the early, mostly premenopausal age at breast cancer diagnosis is suggestive of an inherited predisposition.MethodsHigh-risk cancer cases of non-Jewish origin… read more here.
Keywords: breast; predisposition; breast ovarian; ovarian cancer ... See more keywords
Genetic Predisposition and its Heredity in the Context of Increased Prevalence of Dermatophytoses
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DOI: 10.1007/s11046-021-00529-1
Abstract: Dermatophytosis is a widespread disease with high prevalence and a substantial economic burden associated with costs of treatment. The pattern of this infectious disease covers a wide spectrum from exposed individuals without symptoms to those… read more here.
Keywords: increased prevalence; predisposition; heredity; genetic predisposition ... See more keywords
Familial MPN Predisposition
Sign Up to like & getrecommendations! Published in 2017 at "Current Hematologic Malignancy Reports"
DOI: 10.1007/s11899-017-0414-x
Abstract: Chronic myeloproliferative neoplasms (MPN) characteristically arise from a somatic mutation in the pluripotent hematopoietic stem cell, and most common recurring mutations are in the JAK2, CALR, and cMPL genes. However, these mutations are not founder… read more here.
Keywords: familial mpn; predisposition; mpn predisposition;
Whole-exome sequencing of familial esophageal squamous cell carcinoma identified rare pathogenic variants in new predisposition genes
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Translational Oncology"
DOI: 10.1007/s12094-019-02174-z
Abstract: Purpose Esophageal squamous cell carcinoma (ESCC) is one of the most important causes of mortality in the developing world. Although hereditary forms arise from germ-line mutations in TP53 , Rb , and the mismatch repair… read more here.
Keywords: cell; cell carcinoma; squamous cell; predisposition ... See more keywords
IL-6, IL-8 and IL-10 polymorphisms may impact predisposition of Alzheimer’s disease: a meta-analysis
Sign Up to like & getrecommendations! Published in 2020 at "Acta Neurologica Belgica"
DOI: 10.1007/s13760-020-01369-4
Abstract: Gene polymorphisms in interleukin-6 (IL-6), interleukin-8 (IL-8), and interleukin-10 (IL-10) may affect the predisposition of Alzheimer’s disease (AD), but the results of the so far published studies remain controversial. The authors conducted this meta-analysis to… read more here.
Keywords: predisposition alzheimer; polymorphisms may; predisposition; meta analysis ... See more keywords
Genetic factors associated with the predisposition to late onset Alzheimer's disease.
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DOI: 10.1016/j.gene.2019.05.030
Abstract: BACKGROUND Alzheimer's disease is a progressive, irreversible neurodegenerative disorder characterized by loss of memory and cognitive skills. More than 90% of cases are sporadic and have later age of onset. Many studies have shown a… read more here.
Keywords: alzheimer disease; age; predisposition; mthfr ... See more keywords
Genetic Predisposition to Myelodysplastic Syndrome in Clinical Practice.
Sign Up to like & getrecommendations! Published in 2020 at "Hematology/oncology clinics of North America"
DOI: 10.1016/j.hoc.2019.10.002
Abstract: Myelodysplastic syndromes (MDSs) are a heterogeneous group of marrow failure disorders that primarily affect older persons but also occur at a lower frequency in children and young adults. There is increasing recognition of an inherited… read more here.
Keywords: predisposition; myelodysplastic syndrome; predisposition myelodysplastic; genetic predisposition ... See more keywords