Relating to the Body Under Chronic Cancer Threat: Implications for Psychosocial Health Among Adolescents and Young Adults with Cancer Predisposition Syndromes
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Adolescent and Young Adult Oncology"
DOI: 10.1089/jayao.2024.0103
Abstract: Purpose: Adolescents and young adults (AYAs) with cancer predisposition syndromes often experience significant physical and psychosocial burdens. These burdens include cancer worry and potentially distressing bodily changes due to risk-reducing procedures (e.g., mastectomy) or cancer… read more here.
Keywords: cancer; cancer predisposition; body; health ... See more keywords
Genetic predisposition to cancers in children and adolescents
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Pediatrics"
DOI: 10.1097/mop.0000000000001197
Abstract: Purpose of review Childhood cancer is rare, but it remains the leading cause of disease-related mortality among children 1–14 years of age. As exposure to environmental factors is lower in children, inherited genetic factors become an… read more here.
Keywords: predisposition syndromes; predisposition; predisposition cancers; genetic predisposition ... See more keywords
Inherited predisposition to haematopoietic malignancies: overcoming barriers and exploring opportunities
Sign Up to like & getrecommendations! Published in 2020 at "British Journal of Haematology"
DOI: 10.1111/bjh.17247
Abstract: Inherited predisposition to haematopoietic malignancies, due to deleterious germline variants in a variety of genes, is an important clinical entity with implications for the health and management of patients and their family members. Unfortunately, there… read more here.
Keywords: malignancies overcoming; predisposition; haematopoietic malignancies; predisposition haematopoietic ... See more keywords
Adaptive Psychosocial Outcomes in Cancer Predisposition Syndromes: A Scoping Review.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of adolescent and young adult oncology"
DOI: 10.1177/21565333251366387
Abstract: An increasing number of cancer predisposition syndromes (CPSs) have been associated with childhood cancer in light of advent advances in genomic medicine. While children and adolescents with CPSs present with compounded medical and psychosocial sequalae… read more here.
Keywords: cancer predisposition; adaptive psychosocial; psychosocial outcomes; scoping review ... See more keywords
Pediatric High Grade Gliomas in the Context of Cancer Predisposition Syndromes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Korean Neurosurgical Society"
DOI: 10.3340/jkns.2018.0031
Abstract: Germline mutations in cancer causing genes result in high risk of developing cancer throughout life. These cancer predisposition syndromes (CPS) are especially prevalent in childhood brain tumors and impact both the patient’s and other family… read more here.
Keywords: pediatric high; high grade; cancer predisposition; grade gliomas ... See more keywords
Nonmalignant Features Associated with Inherited Colorectal Cancer Syndromes-Clues for Diagnosis
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DOI: 10.3390/cancers14030628
Abstract: Simple Summary Familiarity with nonmalignant features and comorbidities of cancer predisposition syndromes may raise awareness and assist clinicians in the diagnosis and interpretation of molecular test results. Genetic predisposition to colorectal cancer (CRC) should be… read more here.
Keywords: predisposition syndromes; nonmalignant features; diagnosis; colorectal cancer ... See more keywords
Diagnostic Strategies and Algorithms for Investigating Cancer Predisposition Syndromes in Children Presenting with Malignancy
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DOI: 10.3390/cancers14153741
Abstract: Simple Summary Here we provide an overview of several genetically determined conditions that predispose to the development of solid and hematologic malignancies in children. Diagnosing these conditions, whose prevalence is estimated around 10% in children… read more here.
Keywords: predisposition syndromes; clinical screening; screening tools; cancer predisposition ... See more keywords
Genomic Newborn Screening for Pediatric Cancer Predisposition Syndromes: A Holistic Approach
Sign Up to like & getrecommendations! Published in 2024 at "Cancers"
DOI: 10.3390/cancers16112017
Abstract: Simple Summary Overall, this review offers a comprehensive and insightful exploration of the significance, implementation, and challenges of genomic newborn screening for pediatric cancer predisposition syndromes (CPSs). It emphasizes the importance of next-generation sequencing (NGS)… read more here.
Keywords: newborn screening; cancer; cancer predisposition; pediatric cancer ... See more keywords