Computational studies reveal mechanism by which quinone derivatives can inhibit SARS-CoV-2. Study of embelin and two therapeutic compounds of interest, methyl prednisolone and dexamethasone
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Infection and Public Health"
DOI: 10.1016/j.jiph.2020.09.015
Abstract: Background Quinones are reactive to proteins containing cysteine residues and the main protease in Covid-19 contains an active site that includes Cys145. Embelin, a quinone natural product, is known to have antiviral activity against influenza… read more here.
Keywords: prednisolone dexamethasone; quinone; methyl prednisolone; prednisolone ... See more keywords
Comparison of Hydrocortisone Continuous Rate Infusion and Prednisolone or Dexamethasone Administration for Treatment of Acute Hypoadrenocortical (Addisonian) Crisis in Dogs
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DOI: 10.3389/fvets.2021.818515
Abstract: Objectives To determine whether administration of intravenous hydrocortisone is a safe and effective alternative treatment in comparison to the traditional treatment with prednisolone/dexamethasone in dogs presenting with Addisonian crisis; and to assess if there is… read more here.
Keywords: treated dogs; prednisolone; hydrocortisone; prednisolone dexamethasone ... See more keywords