Urinary excretion profile of prednisone and prednisolone after different administration routes.
Sign Up to like & getrecommendations! Published in 2019 at "Drug testing and analysis"
DOI: 10.1002/dta.2733
Abstract: The urinary excretion profile of prednisolone and prednisone after both systemic (i.e., oral) and topical (i.e., ocular and intranasal) administration was studied by liquid chromatography coupled to mass spectrometry, also to select the most appropriate… read more here.
Keywords: prednisone; administration; prednisone prednisolone; prednisolone ... See more keywords
Carbon isotopic characterization of prednisolone and prednisone pharmaceutical formulations: implications in antidoping analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Drug testing and analysis"
DOI: 10.1002/dta.2876
Abstract: Twenty-two pharmaceutical formulations containing prednisolone or prednisone commercially available in Italy, Belgium, Spain, Brazil, and India, were analyzed through a specific gas chromatography combustion isotope ratio mass spectrometry, GC-C-IRMS, method. All of them showed typical… read more here.
Keywords: prednisone; pharmaceutical formulations; analysis carbon; prednisolone prednisone ... See more keywords
Urinary excretion profile of prednisolone and prednisone after rectal administration: Significance in antidoping analysis
Sign Up to like & getrecommendations! Published in 2022 at "Drug Testing and Analysis"
DOI: 10.1002/dta.3352
Abstract: Abstract The rectal administration of glucocorticoids, as well as any injectable, and oral ones, is currently prohibited by the World Anti‐Doping Agency when occurs “in competition.” A reporting level of 100 ng/ml for prednisolone and 300 ng/ml… read more here.
Keywords: prednisolone; administration; prednisone; urinary excretion ... See more keywords
Going Third Class: Treatment of Steroid-Dependent Ulcerative Colitis
Sign Up to like & getrecommendations! Published in 2019 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-019-05610-w
Abstract: A 28-year-old man with a history of ulcerative colitis (UC) underwent specialist consultation in order to determine the appropriate medical therapy needed to optimally treat his disease. His UC diagnosis occurred 4 years prior to… read more here.
Keywords: prednisone; going third; colitis; ulcerative colitis ... See more keywords
Autoconversion of Autoimmune Liver Diseases
Sign Up to like & getrecommendations! Published in 2019 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-019-05794-1
Abstract: A 38-year-old woman with morbid obesity, gastroesophageal reflux disease, and seronegative rheumatoid arthritis that were treated with sulfasalazine and hydroxychloroquine was referred to our gastroenterology and hepatology clinic for evaluation of abnormal liver function tests… read more here.
Keywords: prednisone; pbc; treatment; gastroenterology ... See more keywords
Repeated pulses of methyl-prednisolone with reduced doses of prednisone improve the outcome of class III, IV and V lupus nephritis: An observational comparative study of the Lupus-Cruces and lupus-Bordeaux cohorts.
Sign Up to like & getrecommendations! Published in 2017 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2017.05.017
Abstract: OBJECTIVE To compare the clinical course of patients with class III, IV and V lupus nephritis (LN) treated at Hospital Universitario Cruces (CC) and at Bordeaux University Hospital (BC). METHODS The Lupus-Cruces nephritis protocol combines… read more here.
Keywords: prednisone; methyl prednisolone; lupus nephritis; lupus cruces ... See more keywords
Sirolimus Vs. Prednisone As Initial Systemic Therapy for Minnesota Standard Risk (MN-SR), Ann Arbor 1/2 Acute Graft-Vs-Host Disease (GVHD): Primary Results of the Multi-Center Randomized Phase II BMT CTN 1501 Trial
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2018.12.128
Abstract: Clinical- and biomarker-based stratification tools may identify a lower risk acute GVHD population amenable to novel, reduced intensity treatments. Previous retrospective data suggest sirolimus, a steroid-free primary therapy, may rival standard of care prednisone. We… read more here.
Keywords: prednisone; sirolimus prednisone; risk; day ... See more keywords
Docetaxel and prednisone with or without enzalutamide as first-line treatment in patients with metastatic castration-resistant prostate cancer: CHEIRON, a randomised phase II trial.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of cancer"
DOI: 10.1016/j.ejca.2021.06.016
Abstract: BACKGROUND Pre-clinical data suggest that docetaxel and enzalutamide interfere with androgen receptor translocation and signalling. The aim of this study is to assess the efficacy of their concurrent administration in the first-line treatment for metastatic… read more here.
Keywords: prednisone; first line; treatment; line treatment ... See more keywords
Therapeutic and antiproteinuric effects of salvianolic acid A in combined with low-dose prednisone in minimal change disease rats: Involvement of PPARγ/Angptl4 and Nrf2/HO-1 pathways.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.04.023
Abstract: Danshen (Salvia miltiorrhiza) and prednisone are extensively applied in the treatment of kidney disease. Salvianolic acid A (SAA), the major biologically active component of Danshen, which has various biological effects. Our previous findings have demonstrated… read more here.
Keywords: prednisone; ppar angptl4; low dose; disease ... See more keywords
Biotransformation of prednisone and dexamethasone by cytochrome P450 based systems - Identification of new potential drug candidates.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biotechnology"
DOI: 10.1016/j.jbiotec.2016.12.011
Abstract: Prednisone and dexamethasone are synthetic glucocorticoids widely used as anti-inflammatory and immunosuppressive drugs. Since their hydroxylated derivatives could serve as novel potential drug candidates, our aim was to investigate their biotransformation by the steroid hydroxylase… read more here.
Keywords: prednisone; drug candidates; prednisone dexamethasone; potential drug ... See more keywords
Acute serum protein and cytokine response of single dose of prednisone in adult volunteers
Sign Up to like & getrecommendations! Published in 2022 at "Steroids"
DOI: 10.1016/j.steroids.2021.108953
Abstract: Pharmacological glucocorticoids are the most prescribed anti-inflammatory medications, and are chemical variants of cortisol, the circadian and stress hormone. Both endogenous and pharmacological glucocorticoids bind the glucocorticoid receptor (NR3C1) with high affinity, and both then… read more here.
Keywords: response single; adult volunteers; single dose; dose ... See more keywords