Anti-cytomegalovirus preemptive therapy to prevent cytomegalovirus disease in HIV-infected patients: a systematic review
Sign Up to like & getrecommendations! Published in 2023 at "Infectious Diseases"
DOI: 10.1080/23744235.2023.2165708
Abstract: Abstract Background HIV patients are at higher risk of contracting and developing into an asymptomatic form of CMV infection. This review aimed to evaluate the efficacy and safety of preemptive therapy for preventing CMV disease… read more here.
Keywords: hiv; review; disease; therapy ... See more keywords
Cost-effectiveness of single-dose AmBisome preemptive treatment for the prevention of cryptococcal meningitis in African low and middle-income countries.
Sign Up to like & getrecommendations! Published in 2022 at "Medical mycology"
DOI: 10.1093/mmy/myab078
Abstract: Cryptococcal antigen (CrAg) screening is recommended for patients with advanced HIV to reduce AIDS-related mortality. For asymptomatic CrAg-positive persons, fluconazole preemptive therapy is standard, despite a ∼25% failure rate. Single-dose liposomal amphotericin B (AmBisome) is… read more here.
Keywords: cost; efficacy; preemptive therapy; middle income ... See more keywords
Cytomegalovirus infection and disease in pediatric liver transplantation: Burden of disease under a preemptive therapy approach
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DOI: 10.1111/petr.14356
Abstract: CMV remains a frequent complication after liver transplantation. Few studies exist in children reporting the epidemiology and outcomes of CMV after LT with current prevention strategies. Our goal is to report the incidence of CMV… read more here.
Keywords: infection disease; disease; disease pediatric; preemptive therapy ... See more keywords
Real‐world effectiveness of preemptive therapy (PET) for cytomegalovirus (CMV) disease prevention in CMV high‐risk donor seropositive/recipient seronegative (D+R‐) liver transplant recipients (LTxR)
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DOI: 10.1111/tid.14015
Abstract: Despite superiority of preemptive therapy (PET) compared to universal prophylaxis for prevention of cytomegalovirus (CMV) disease in the CAPSIL randomized trial among CMV D+R‐ liver transplant recipients (LTxRs), real‐world effectiveness may be lower because of… read more here.
Keywords: disease; pet; therapy pet; preemptive therapy ... See more keywords
Population Pharmacokinetic and Pharmacodynamic Analysis of Valganciclovir for Optimizing Preemptive Therapy of Cytomegalovirus Infections in Kidney Transplant Recipients
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DOI: 10.1128/aac.01665-22
Abstract: This study aimed to develop a population pharmacokinetic/pharmacodynamic (PK/PD) model of valganciclovir for preemptive therapy of cytomegalovirus (CMV) infection in kidney transplant patients. A population PK/PD model was developed with Monolix. ABSTRACT This study aimed… read more here.
Keywords: viral load; preemptive therapy; kidney transplant; model ... See more keywords