The K-Ras, N-Ras, and H-Ras Isoforms: Unique Conformational Preferences and Implications for Targeting Oncogenic Mutants.
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DOI: 10.1101/cshperspect.a031427
Abstract: Ras controls a multitude of cellular signaling processes, including cell proliferation, differentiation, and apoptosis. Deregulation of Ras cycling often promotes tumorigenesis and various other developmental disorders, termed RASopothies. Although the structure of Ras has been… read more here.
Keywords: preferences implications; conformational preferences; ras ras; isoforms unique ... See more keywords