Alternative lengthening of telomeres can be maintained by preferential elongation of lagging strands
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DOI: 10.1093/nar/gkw1295
Abstract: Abstract Alternative lengthening of telomeres (ALT) is a telomerase independent telomere maintenance mechanism that occurs in ∼15% of cancers. The potential mechanism of ALT is homology-directed telomere synthesis, but molecular mechanisms of how ALT maintains… read more here.
Keywords: alternative lengthening; telomerase positive; elongation; preferential elongation ... See more keywords